Targeting Oxidatively Induced DNA Damage Response in Cancer: Opportunities for Novel Cancer Therapies

by Davalli, Pierpaola, Marverti, Gaetano, Lauriola, Angela, D'Arca, Domenico
Published in Oxid Med Cell Longev (2018)

ROS, Cell Senescence, and Novel Molecular Mechanisms in Aging and Age-Related Diseases

by Davalli, Pierpaola, Mitic, Tijana, Caporali, Andrea, Lauriola, Angela, D'Arca, Domenico
Published in Oxid Med Cell Longev (2016)

Huwe1 ubiquitin ligase is essential to synchronize neuronal and glial differentiation in the developing cerebellum

by D’Arca, Domenico, Zhao, Xudong, Xu, Wenming, Ramirez-Martinez, Nadya C., Iavarone, Antonio, Lasorella, Anna
Published 2010

Involvement of epigenetic modification of TERT promoter in response to all-trans retinoic acid in ovarian cancer cell lines

by Losi, Lorena, Lauriola, Angela, Tazzioli, Erica, Gozzi, Gaia, Scurani, Letizia, D’Arca, Domenico, Benhattar, Jean
Published in J Ovarian Res (2019)

Anticancer Activity of Green Tea Polyphenols in Prostate Gland

by Davalli, Pierpaola, Rizzi, Federica, Caporali, Andrea, Pellacani, Davide, Davoli, Serena, Bettuzzi, Saverio, Brausi, Maurizio, D'Arca, Domenico
Published 2012

Cell detachment and apoptosis induction of immortalized human prostate epithelial cells are associated with early accumulation of a 45 kDa nuclear isoform of clusterin

by Caccamo, Alessandro E., Scaltriti, Maurizio, Caporali, Andrea, D'Arca, Domenico, Scorcioni, Francesca, Astancolle, Serenella, Mangiola, Massimo, Bettuzzi, Saverio
Published 2004

The 1,10-Phenanthroline Ligand Enhances the Antiproliferative Activity of DNA-Intercalating Thiourea-Pd(II) and -Pt(II) Complexes Against Cisplatin-Sensitive and -Resistant Human O...

by Marverti, Gaetano, Gozzi, Gaia, Lauriola, Angela, Ponterini, Glauco, Belluti, Silvia, Imbriano, Carol, Costi, Maria Paola, D’Arca, Domenico
Published in Int J Mol Sci (2019)

Depletion of Trichoplein (TpMs) Causes Chromosome Mis-Segregation, DNA Damage and Chromosome Instability in Cancer Cells

by Lauriola, Angela, Martello, Andrea, Fantini, Sebastian, Marverti, Gaetano, Zanocco-Marani, Tommaso, Davalli, Pierpaola, Guardavaccaro, Daniele, Mai, Sabine, Caporali, Andrea, D’Arca, Domenico
Published in Cancers (Basel) (2020)

Repurposing of Drugs Targeting YAP-TEAD Functions

by Elisi, Gian Marco, Santucci, Matteo, D’Arca, Domenico, Lauriola, Angela, Marverti, Gaetano, Losi, Lorena, Scalvini, Laura, Bolognesi, Maria Laura, Mor, Marco, Costi, Maria Paola
Published in Cancers (Basel) (2018)

Cyclic Peptides Acting as Allosteric Inhibitors of Human Thymidylate Synthase and Cancer Cell Growth

by Pacifico, Salvatore, Santucci, Matteo, Luciani, Rosaria, Saxena, Puneet, Linciano, Pasquale, Ponterini, Glauco, Lauriola, Angela, D’Arca, Domenico, Marverti, Gaetano, Guerrini, Remo, Costi, Maria Paola
Published in Molecules (2019)

Structural Bases for the Synergistic Inhibition of Human Thymidylate Synthase and Ovarian Cancer Cell Growth by Drug Combinations

by Pozzi, Cecilia, Santucci, Matteo, Marverti, Gaetano, D’Arca, Domenico, Tagliazucchi, Lorenzo, Ferrari, Stefania, Gozzi, Gaia, Losi, Lorena, Tassone, Giusy, Mangani, Stefano, Ponterini, Glauco, Costi, Maria Paola
Published in Cancers (Basel) (2021)

Intracellular quantitative detection of human thymidylate synthase engagement with an unconventional inhibitor using tetracysteine-diarsenical-probe technology

by Ponterini, Glauco, Martello, Andrea, Pavesi, Giorgia, Lauriola, Angela, Luciani, Rosaria, Santucci, Matteo, Pelà, Michela, Gozzi, Gaia, Pacifico, Salvatore, Guerrini, Remo, Marverti, Gaetano, Costi, Maria Paola, D’Arca, Domenico
Published in Sci Rep (2016)

A Peptidic Thymidylate-Synthase Inhibitor Loaded on Pegylated Liposomes Enhances the Antitumour Effect of Chemotherapy Drugs in Human Ovarian Cancer Cells

by Marverti, Gaetano, Gozzi, Gaia, Maretti, Eleonora, Lauriola, Angela, Severi, Leda, Sacchetti, Francesca, Losi, Lorena, Pacifico, Salvatore, Ferrari, Stefania, Ponterini, Glauco, Leo, Eliana, Costi, Maria Paola, D’Arca, Domenico
Published in Int J Mol Sci (2020)

Mitostatin Is Down-Regulated in Human Prostate Cancer and Suppresses the Invasive Phenotype of Prostate Cancer Cells

by Fassan, Matteo, D'Arca, Domenico, Letko, Juraj, Vecchione, Andrea, Gardiman, Marina P., McCue, Peter, Wildemore, Bernadette, Rugge, Massimo, Shupp-Byrne, Dolores, Gomella, Leonard G., Morrione, Andrea, Iozzo, Renato V., Baffa, Raffaele
Published 2011

Trichoplein binds PCM1 and controls endothelial cell function by regulating autophagy

by Martello, Andrea, Lauriola, Angela, Mellis, David, Parish, Elisa, Dawson, John C, Imrie, Lisa, Vidmar, Martina, Gammoh, Noor, Mitić, Tijana, Brittan, Mairi, Mills, Nicholas L, Carragher, Neil O, D'Arca, Domenico, Caporali, Andrea
Published in EMBO Rep (2020)

Folic Acid–Peptide Conjugates Combine Selective Cancer Cell Internalization with Thymidylate Synthase Dimer Interface Targeting

by Marverti, Gaetano, Marraccini, Chiara, Martello, Andrea, D’Arca, Domenico, Pacifico, Salvatore, Guerrini, Remo, Spyrakis, Francesca, Gozzi, Gaia, Lauriola, Angela, Santucci, Matteo, Cannazza, Giuseppe, Tagliazucchi, Lorenzo, Cazzato, Addolorata Stefania, Losi, Lorena, Ferrari, Stefania, Ponterini, Glauco, Costi, Maria P.
Published in J Med Chem (2021)

Proteomic and Bioinformatic Studies for the Characterization of Response to Pemetrexed in Platinum Drug Resistant Ovarian Cancer

by Severi, Leda, Losi, Lorena, Fonda, Sergio, Taddia, Laura, Gozzi, Gaia, Marverti, Gaetano, Magni, Fulvio, Chinello, Clizia, Stella, Martina, Sheouli, Jalid, Braicu, Elena I., Genovese, Filippo, Lauriola, Angela, Marraccini, Chiara, Gualandi, Alessandra, D'Arca, Domenico, Ferrari, Stefania, Costi, Maria P.
Published in Front Pharmacol (2018)