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The 1,10-Phenanthroline Ligand Enhances the Antiproliferative Activity of DNA-Intercalating Thiourea-Pd(II) and -Pt(II) Complexes Against Cisplatin-Sensitive and -Resistant Human Ovarian Cancer Cell Lines

Ovarian cancer is the most lethal gynecological malignancy, often because of the frequent insurgence of chemoresistance to the drugs currently used. Thus, new therapeutical agents are needed. We tested the toxicity of 16 new DNA-intercalating agents to cisplatin (cDDP)-sensitive human ovarian carcin...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Marverti, Gaetano, Gozzi, Gaia, Lauriola, Angela, Ponterini, Glauco, Belluti, Silvia, Imbriano, Carol, Costi, Maria Paola, D’Arca, Domenico
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6969938/
https://ncbi.nlm.nih.gov/pubmed/31817267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms20246122
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