Depletion of Trichoplein (TpMs) Causes Chromosome Mis-Segregation, DNA Damage and Chromosome Instability in Cancer Cells

Mitotic perturbations frequently lead to chromosome mis-segregation that generates genome instability, thereby triggering tumor onset and/or progression. Error-free mitosis depends on fidelity-monitoring systems that ensure the temporal and spatial coordination of chromosome segregation. Recent inve...

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Publicado en:Cancers (Basel)
Autores principales: Lauriola, Angela, Martello, Andrea, Fantini, Sebastian, Marverti, Gaetano, Zanocco-Marani, Tommaso, Davalli, Pierpaola, Guardavaccaro, Daniele, Mai, Sabine, Caporali, Andrea, D’Arca, Domenico
Formato: Artigo
Lenguaje:Inglês
Publicado: MDPI 2020
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC7226535/
https://ncbi.nlm.nih.gov/pubmed/32316593
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cancers12040993
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