Role of Cystatin C in Neuroprotection and Its Therapeutic Implications

Por D'Adamio, Luciano
Publicado em 2010

Memory Deficits of British Dementia Knock-In Mice Are Prevented by Aβ-Precursor Protein Haploinsufficiency

Por Tamayev, Robert, D'Adamio, Luciano
Publicado em 2012

Inhibition of γ-secretase worsens memory deficits in a genetically congruous mouse model of Danish dementia

Por Tamayev, Robert, D’Adamio, Luciano
Publicado em 2012

Presenilin-ryanodine receptor connection

Por D’Adamio, Luciano, Castillo, Pablo E.
Publicado em 2013

Trem2 Splicing and Expression are Preserved in a Human Aβ-producing, Rat Knock-in Model of Trem2-R47H Alzheimer’s Risk Variant

Por Tambini, Marc D., D’Adamio, Luciano
Publicado no Sci Rep (2020)

Knock-in rats with homozygous PSEN1(L435F) Alzheimer mutation are viable and show selective γ-secretase activity loss causing low Aβ40/42 and high Aβ43

Por Tambini, Marc D., D'Adamio, Luciano
Publicado no J Biol Chem (2020)

The interactome of the amyloid β precursor protein family members is shaped by phosphorylation of their intracellular domains

Por D'Adamio Luciano, Zhou Dawang, Tamayev Robert
Publicado em 2009-07-01

BRI3 Inhibits Amyloid Precursor Protein Processing in a Mechanistically Distinct Manner from Its Homologue Dementia Gene BRI2

Por Matsuda, Shuji, Matsuda, Yukiko, D'Adamio, Luciano
Publicado em 2009

The interactome of the amyloid β precursor protein family members is shaped by phosphorylation of their intracellular domains

Por Tamayev, Robert, Zhou, Dawang, D'Adamio, Luciano
Publicado em 2009

CD74 interacts with APP and suppresses the production of Aβ

Por Matsuda, Shuji, Matsuda, Yukiko, D'Adamio, Luciano
Publicado em 2009

β - but not γ-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia

Por Tamayev, Robert, Matsuda, Shuji, D’Adamio, Luciano
Publicado em 2012

Increased AβPP Processing in Familial Danish Dementia Patients

Por Matsuda, Shuji, Tamayev, Robert, D’Adamio, Luciano
Publicado em 2011

JNK-interacting protein-1 promotes transcription of Aβ protein precursor but not Aβ precursor-like proteins, mechanistically different than Fe65

Por Scheinfeld, Meir H., Matsuda, Shuji, D'Adamio, Luciano
Publicado em 2003

Facilitation of glutamate, but not GABA, release in Familial Alzheimer's APP mutant Knock‐in rats with increased β‐cleavage of APP

Por Tambini, Marc D., Yao, Wen, D'Adamio, Luciano
Publicado no Aging Cell (2019)

Significance of Blood and Cerebrospinal Fluid Biomarkers for Alzheimer’s Disease: Sensitivity, Specificity and Potential for Clinical Use

Por d’Abramo, Cristina, D’Adamio, Luciano, Giliberto, Luca
Publicado no J Pers Med (2020)

Generation and Initial Characterization of FDD Knock In Mice

Por Giliberto, Luca, Matsuda, Shuji, Vidal, Ruben, D'Adamio, Luciano
Publicado em 2009

β- but not γ-secretase proteolysis of APP causes synaptic and memory deficits in a mouse model of dementia

Por Tamayev, Robert, Matsuda, Shuji, Arancio, Ottavio, D'Adamio, Luciano
Publicado em 2012

Opposite changes in APP processing and human Aβ levels in rats carrying either a protective or a pathogenic APP mutation

Por Tambini, Marc D, Norris, Kelly A, D'Adamio, Luciano
Publicado no eLife (2020)

A Role for Neutral Sphingomyelinase-mediated Ceramide Production in T Cell Receptor–induced Apoptosis and Mitogen-activated Protein Kinase–mediated Signal Transduction

Por Tonnetti, Laura, Verí, Maria-Concetta, Bonvini, Ezio, D'Adamio, Luciano
Publicado em 1999

Maturation of BRI2 generates a specific inhibitor that reduces APP processing at the plasma membrane and in endocytic vesicles

Por Matsuda, Shuji, Matsuda, Yukiko, Snapp, Erik L., D’Adamio, Luciano
Publicado em 2009