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Increased AβPP Processing in Familial Danish Dementia Patients
An autosomal dominant mutation in the BRI2/ITM2B gene causes Familial Danish Dementia (FDD). We have generated a mouse model of FDD, called FDD(KI), genetically congruous to the human disease. These mice carry one mutant and one wild type Bri2/Itm2b allele, like FDD patients. Analysis of FDD(KI) mic...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3690758/ https://ncbi.nlm.nih.gov/pubmed/21841249 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3233/JAD-2011-110785 |
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