The Rho GTPase Effector ROCK Regulates Cyclin A, Cyclin D1, and p27(Kip1) Levels by Distinct Mechanisms

Por Croft, Daniel R., Olson, Michael F.
Publicado em 2006

Transcriptional regulation of Rho GTPase signaling

Por Croft, Daniel R, Olson, Michael F
Publicado em 2011

Actin-myosin–based contraction is responsible for apoptotic nuclear disintegration

Por Croft, Daniel R., Coleman, Mathew L., Li, Shuixing, Robertson, David, Sullivan, Teresa, Stewart, Colin L., Olson, Michael F.
Publicado em 2005

The cyclin-dependent kinase PITSLRE/CDK11 is required for successful autophagy

Por Wilkinson, Simon, Croft, Daniel R, O'Prey, Jim, Meedendorp, Arenda, O'Prey, Margaret, Dufès, Christine, Ryan, Kevin M
Publicado em 2011

AP-1 Differentially Expressed Proteins Krp1 and Fibronectin Cooperatively Enhance Rho-ROCK-Independent Mesenchymal Invasion by Altering the Function, Localization, and Activity of...

Por Spence, Heather J., McGarry, Lynn, Chew, Catherine S., Carragher, Neil O., Scott-Carragher, Linda A., Yuan, Zhengqiang, Croft, Daniel R., Olson, Michael F., Frame, Margaret, Ozanne, Bradford W.
Publicado em 2006

p53-mediated transcriptional regulation and activation of the actin cytoskeleton regulatory RhoC to LIMK2 signaling pathway promotes cell survival

Por Croft, Daniel R, Crighton, Diane, Samuel, Michael S, Lourenco, Filipe C, Munro, June, Wood, Jenifer, Bensaad, Karim, Vousden, Karen H, Sansom, Owen J, Ryan, Kevin M, Olson, Michael F
Publicado em 2011

A novel small-molecule MRCK inhibitor blocks cancer cell invasion

Por Unbekandt, Mathieu, Croft, Daniel R, Crighton, Diane, Mezna, Mokdad, McArthur, Duncan, McConnell, Patricia, Schüttelkopf, Alexander W, Belshaw, Simone, Pannifer, Andrew, Sime, Mairi, Bower, Justin, Drysdale, Martin, Olson, Michael F
Publicado em 2014

LIM kinases are required for invasive path generation by tumor and tumor-associated stromal cells

Por Scott, Rebecca W., Hooper, Steven, Crighton, Diane, Li, Ang, König, Ireen, Munro, June, Trivier, Elisabeth, Wickman, Grant, Morin, Pierre, Croft, Daniel R., Dawson, John, Machesky, Laura, Anderson, Kurt I., Sahai, Erik A., Olson, Michael F.
Publicado em 2010

Loss of autophagy causes a synthetic lethal deficiency in DNA repair

Por Liu, Emma Y., Xu, Naihan, O’Prey, Jim, Lao, Laurence Y., Joshi, Sanket, Long, Jaclyn S., O’Prey, Margaret, Croft, Daniel R., Beaumatin, Florian, Baudot, Alice D., Mrschtik, Michaela, Rosenfeldt, Mathias, Zhang, Yaou, Gillespie, David A., Ryan, Kevin M.
Publicado no Proc Natl Acad Sci U S A (2015)

Actomyosin-mediated cellular tension drives increased tissue stiffness and β-catenin activation to induce interfollicular epidermal hyperplasia and tumor growth

Por Samuel, Michael S, Lopez, Jose I, McGhee, Ewan J, Croft, Daniel R, Strachan, David, Timpson, Paul, Munro, June, Schröder, Ewald, Zhou, Jing, Brunton, Valerie G, Barker, Nick, Clevers, Hans, Sansom, Owen J, Anderson, Kurt I, Weaver, Valerie M, Olson, Michael F
Publicado em 2011

LIM kinase inhibitors disrupt mitotic microtubule organization and impair tumor cell proliferation

Por Mardilovich, Katerina, Baugh, Mark, Crighton, Diane, Kowalczyk, Dominika, Gabrielsen, Mads, Munro, June, Croft, Daniel R., Lourenco, Filipe, James, Daniel, Kalna, Gabriella, McGarry, Lynn, Rath, Oliver, Shanks, Emma, Garnett, Mathew J., McDermott, Ultan, Brookfield, Joanna, Charles, Mark, Hammonds, Tim, Olson, Michael F.
Publicado no Oncotarget (2015)