IGF-1 and Bone: New Discoveries From Mouse Models

Por Yakar, Shoshana, Courtland, Hayden-William, Clemmons, David
Publicado em 2010

Genetically Determined Phenotype Covariation Networks Control Bone Strength

Por Jepsen, Karl J, Courtland, Hayden-William, Nadeau, Joseph H
Publicado em 2010

Genetic Variation in Mouse Femoral Tissue-Level Mineral Content Underlies Differences in Whole Bone Mechanical Properties

Por Courtland, Hayden-William, Spevak, Mila, Boskey, Adele L., Jepsen, Karl J.
Publicado em 2008

Fourier Transform Infrared Imaging Microspectroscopy and Tissue-Level Mechanical Testing Reveal Intraspecies Variation in Mouse Bone Mineral and Matrix Composition

Por Courtland, Hayden-William, Nasser, Philip, Goldstone, Andrew B., Spevak, Lyudmila, Boskey, Adele L., Jepsen, Karl J.
Publicado em 2008

Sex‐specific regulation of body size and bone slenderness by the acid labile subunit

Por Courtland, Hayden‐William, DeMambro, Victoria, Maynard, Jane, Sun, Hui, Elis, Sebastien, Rosen, Clifford, Yakar, Shoshana
Publicado em 2010

Growth Hormone Mediates Pubertal Skeletal Development Independent of Hepatic IGF-1 Production

Por Courtland, Hayden-William, Sun, Hui, Beth-On, Mordechay, Wu, Yingjie, Elis, Sebastien, Rosen, Clifford J, Yakar, Shoshana
Publicado em 2011

Serum IGF-1 Affects Skeletal Acquisition in a Temporal and Compartment-Specific Manner

Por Courtland, Hayden-William, Elis, Sebastien, Wu, Yingjie, Sun, Hui, Rosen, Clifford J., Jepsen, Karl J., Yakar, Shoshana
Publicado em 2011

Elevated serum IGF‐1 levels synergize PTH action on the skeleton only when the tissue IGF‐1 axis is intact

Por Elis, Sebastien, Courtland, Hayden‐William, Wu, Yingjie, Fritton, J Christopher, Sun, Hui, Rosen, Clifford J, Yakar, Shoshana
Publicado em 2010

Measuring the dynamic mechanical response of hydrated mouse bone by nanoindentation

Por Pathak, Siddhartha, Swadener, J. Gregory, Kalidindi, Surya R., Courtland, Hayden-William, Jepsen, Karl J., Goldman, Haviva M.
Publicado em 2010

Low levels of plasma IGF-1 inhibit intracortical bone remodeling during aging

Por Courtland, Hayden-William, Kennedy, Oran D., Wu, Yingjie, Gao, Ying, Sun, Hui, Schaffler, Mitchell B., Yakar, Shoshana
Publicado em 2012

Phenotypic integration of skeletal traits during growth buffers genetic variants affecting the slenderness of femora in inbred mouse strains

Por Jepsen, Karl J., Hu, Bin, Tommasini, Steven M., Courtland, Hayden-William, Price, Christopher, Cordova, Matthew, Nadeau, Joseph H.
Publicado em 2008

Increased serum IGF-1 levels protect the musculoskeletal system but are associated with elevated oxidative stress markers and increased mortality independent of tissue igf1 gene ex...

Por Elis, Sebastien, Wu, YingJie, Courtland, Hayden-William, Sun, Hui, Rosen, Clifford J, Adamo, Martin L, Yakar, Shoshana
Publicado em 2011

Genetic randomization reveals functional relationships among morphologic and tissue-quality traits that contribute to bone strength and fragility

Por Jepsen, Karl J., Hu, Bin, Tommasini, Steven M., Courtland, Hayden-William, Price, Christopher, Terranova, Carl J., Nadeau, Joseph H.
Publicado em 2007

Elevated Serum Levels of IGF-1 Are Sufficient to Establish Normal Body Size and Skeletal Properties Even in the Absence of Tissue IGF-1

Por Elis, Sebastien, Courtland, Hayden-William, Wu, Yingjie, Rosen, Clifford J, Sun, Hui, Jepsen, Karl J, Majeska, Robert J, Yakar, Shoshana
Publicado em 2010

Fourier Transform Infrared Spectroscopic Imaging of Fracture Healing in the Normal Mouse

Por Gollwitzer, Hans, Yang, Xu, Spevak, Lyudmila, Lukashova, Lyudmila, Nocon, Allina, Fields, Kara, Pleshko, Nancy, Courtland, Hayden William, Bostrom, Mathias P., Boskey, Adele L.
Publicado no J Spectrosc (Hindawi) (2015)

Serum IGF-1 Determines Skeletal Strength by Regulating Subperiosteal Expansion and Trait Interactions

Por Yakar, Shoshana, Canalis, Ernesto, Sun, Hui, Mejia, Wilson, Kawashima, Yuki, Nasser, Philip, Courtland, Hayden-William, Williams, Valerie, Bouxsein, Mary, Rosen, Clifford, Jepsen, Karl J.
Publicado em 2009

Skeletal Response of Male Mice to Anabolic Hormone Therapy in the Absence of the Igfals Gene

Por Kennedy, Oran D., Sun, Hui, Wu, YingJie, Courtland, Hayden-William, Williams, Garry A., Cardoso, Luis, Basta-Pljakic, Jelena, Schaffler, Mitchell B., Yakar, Shoshana
Publicado em 2014

Intermittent PTH administration and mechanical loading are anabolic for periprosthetic cancellous bone

Por Grosso, Matthew J., Courtland, Hayden-William, Yang, Xu, Sutherland, James P., Stoner, Kirsten, Nguyen, Joseph, Fahlgren, Anna, Ross, F. Patrick, van der Meulen, Marjolein C. H., Bostrom, Mathias P.
Publicado no J Orthop Res (2014)

Unbound (bioavailable) IGF1 enhances somatic growth

Por Elis, Sebastien, Wu, Yingjie, Courtland, Hayden-William, Cannata, Dara, Sun, Hui, Beth-On, Mordechay, Liu, Chengyu, Jasper, Hector, Domené, Horacio, Karabatas, Liliana, Guida, Clara, Basta-Pljakic, Jelena, Cardoso, Luis, Rosen, Clifford J., Frystyk, Jan, Yakar, Shoshana
Publicado em 2011

Genetic architecture of complex traits: Large phenotypic effects and pervasive epistasis

Por Shao, Haifeng, Burrage, Lindsay C., Sinasac, David S., Hill, Annie E., Ernest, Sheila R., O'Brien, William, Courtland, Hayden-William, Jepsen, Karl J., Kirby, Andrew, Kulbokas, E. J., Daly, Mark J., Broman, Karl W., Lander, Eric S., Nadeau, Joseph H.
Publicado em 2008