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Sex‐specific regulation of body size and bone slenderness by the acid labile subunit

Insulin‐like growth factor 1 (IGF‐1) is a crucial mediator of body size and bone mass during growth and development. In serum, IGF‐1 is stabilized by several IGF‐1‐binding proteins (IGFBPs) and the acid labile subunit (ALS). Previous research using ALS knockout (ALSKO) mice indicated a growth retard...

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Detalhes bibliográficos
Main Authors: Courtland, Hayden‐William, DeMambro, Victoria, Maynard, Jane, Sun, Hui, Elis, Sebastien, Rosen, Clifford, Yakar, Shoshana
Formato: Artigo
Idioma:Inglês
Publicado em: Wiley Subscription Services, Inc., A Wiley Company 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3118255/
https://ncbi.nlm.nih.gov/pubmed/20499371
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jbmr.94
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