The Insulin-like Growth Factor-1 Binding Protein Acid-labile Subunit Alters Mesenchymal Stromal Cell Fate

Age-related osteoporosis is accompanied by an increase in marrow adiposity and a reduction in serum insulin-like growth factor-1 (IGF-1) and the binding proteins that stabilize IGF-1. To determine the relationship between these proteins and bone marrow adiposity, we evaluated the adipogenic potentia...

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Main Authors: Fritton, J. Christopher, Kawashima, Yuki, Mejia, Wilson, Courtland, Hayden-Williams, Elis, Sebastien, Sun, Hui, Wu, Yinjgie, Rosen, Clifford J., Clemmons, David, Yakar, Shoshana
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Lipids
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2836075/
https://ncbi.nlm.nih.gov/pubmed/20007694
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.041913
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