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Low levels of plasma IGF-1 inhibit intracortical bone remodeling during aging
Studies linking insulin-like growth factor-1 (IGF-1) to age-related bone loss in humans have been reported but remain only correlative. In this investigation, we characterized the bone phenotype of aged WT C57BL/6J male mice in comparison to that of C57BL/6J mice with reduced serum IGF-1 levels aris...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer Netherlands
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3776121/ https://ncbi.nlm.nih.gov/pubmed/22976122 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11357-012-9469-8 |
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