Increased serum IGF-1 levels protect the musculoskeletal system but are associated with elevated oxidative stress markers and increased mortality independent of tissue igf1 gene expression

Although the literature suggests a protective (anabolic) effect of insulin-like growth factor-1 (IGF-1) on the musculoskeletal system during growth and aging, there is evidence that reductions in IGF-1 signaling are advantageous for promoting an increase in lifespan through reduction in oxidative st...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Elis, Sebastien, Wu, YingJie, Courtland, Hayden-William, Sun, Hui, Rosen, Clifford J, Adamo, Martin L, Yakar, Shoshana
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3094487/
https://ncbi.nlm.nih.gov/pubmed/21418509
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1474-9726.2011.00683.x
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky