Calmodulin Antagonizes a Calcium-Activated SCF Ubiquitin E3 Ligase Subunit, FBXL2, To Regulate Surfactant Homeostasis

Autor Chen, Bill B., Coon, Tiffany A., Glasser, Jennifer R., Mallampalli, Rama K.
Vydáno 2011

FBXL2 is a ubiquitin E3 ligase subunit that triggers mitotic arrest

Autor Chen, Bill B, Glasser, Jennifer R, Coon, Tiffany A, Mallampalli, Rama K
Vydáno 2011

F box protein FBXL2 exerts human lung tumor suppressor-like activity by ubiquitin-mediated degradation of cyclin D3 resulting in cell cycle arrest

Autor Chen, Bill B., Glasser, Jennifer R., Coon, Tiffany A., Mallampalli, Rama K.
Vydáno 2011

Novel E3 ligase component FBXL7 ubiquitinates and degrades Aurora A, causing mitotic arrest

Autor Coon, Tiffany A, Glasser, Jennifer R, Mallampalli, Rama K, Chen, Bill B
Vydáno 2012

Calmodulin protects Aurora B on the midbody to regulate the fidelity of cytokinesis

Autor Mallampalli, Rama K., Glasser, Jennifer R., Coon, Tiffany A., Chen, Bill B.
Vydáno 2013

Fbxl12 triggers G1 arrest by mediating degradation of calmodulin kinase I

Autor Mallampalli, Rama K., Kaercher, Leah, Snavely, Courtney, Pulijala, Roopa, Chen, Bill B., Coon, Tiffany, Zhao, Jing, Agassandian, Marianna
Vydáno 2013

Azithromycin decreases NALP3 mRNA stability in monocytes to limit inflammasome-dependent inflammation

Autor Lendermon, Elizabeth A., Coon, Tiffany A., Bednash, Joseph S., Weathington, Nathaniel M., McDyer, John F., Mallampalli, Rama K.
Vydáno v Respir Res (2017)

SCF E3 ligase F-box protein complex SCF(FBXL19) regulates cell migration by mediating Rac1 ubiquitination and degradation

Autor Zhao, Jing, Mialki, Rachel K., Wei, Jianxin, Coon, Tiffany A., Zou, Chunbin, Chen, Bill B., Mallampalli, Rama K., Zhao, Yutong
Vydáno 2013

LPS Impairs Phospholipid Synthesis by Triggering β-Transducin Repeat-containing Protein (β-TrCP)-mediated Polyubiquitination and Degradation of the Surfactant Enzyme Acyl-CoA:Lysop...

Autor Zou, Chunbin, Butler, Phillip L., Coon, Tiffany A., Smith, Rebecca M., Hammen, Gary, Zhao, Yutong, Chen, Bill B., Mallampalli, Rama K.
Vydáno 2011

Novel PDE4 Inhibitors Derived from Chinese Medicine Forsythia

Autor Coon, Tiffany A., McKelvey, Alison C., Weathington, Nate M., Birru, Rahel L., Lear, Travis, Leikauf, George D., Chen, Bill B.
Vydáno v PLoS One (2014)

SCF(Fbxw15) Mediates Histone Acetyltransferase Binding to Origin Recognition Complex (HBO1) Ubiquitin-Proteasomal Degradation to Regulate Cell Proliferation

Autor Zou, Chunbin, Chen, Yan, Smith, Rebecca M., Snavely, Courtney, Li, Jin, Coon, Tiffany A., Chen, Bill B., Zhao, Yutong, Mallampalli, Rama K.
Vydáno 2013

F-box protein FBXL19–mediated ubiquitination and degradation of the receptor for IL-33 limits pulmonary inflammation

Autor Zhao, Jing, Wei, Jianxin, Mialki, Rachel K, Mallampalli, Daniel F, Chen, Bill B, Coon, Tiffany, Zou, Chunbin, Mallampalli, Rama K, Zhao, Yutong
Vydáno 2012

F-box protein FBXL2 targets cyclin D2 for ubiquitination and degradation to inhibit leukemic cell proliferation

Autor Chen, Bill B., Glasser, Jennifer R., Coon, Tiffany A., Zou, Chunbin, Miller, Hannah L., Fenton, Moon, McDyer, John F., Boyiadzis, Michael, Mallampalli, Rama K.
Vydáno 2012

Activation-induced Cell Death Drives Profound Lung CD4(+) T-Cell Depletion in HIV-associated Chronic Obstructive Pulmonary Disease

Autor Popescu, Iulia, Drummond, M. Bradley, Gama, Lucio, Coon, Tiffany, Merlo, Christian A., Wise, Robert A., Clements, Janice E., Kirk, Gregory D., McDyer, John F.
Vydáno v Am J Respir Crit Care Med (2014)

Targeting F box protein Fbxo3 to control cytokine-driven inflammation

Autor Mallampalli, Rama K., Coon, Tiffany A., Glasser, Jennifer R., Wang, Claire, Dunn, Sarah R., Weathington, Nathaniel M., Zhao, Jing, Zou, Chunbin, Zhao, Yutong, Chen, Bill B.
Vydáno 2013

A combinatorial F box protein directed pathway controls TRAF adaptor stability to regulate inflammation

Autor Chen, Bill B., Coon, Tiffany A., Glasser, Jennifer R., McVerry, Bryan J., Zhao, Jing, Zhao, Yutong, Zou, Chunbin, Ellis, Bryon, Sciurba, Frank C., Zhang, Yingze, Mallampalli, Rama K.
Vydáno 2013

Ubiquitin E3 ligase FIEL1 regulates fibrotic lung injury through SUMO-E3 ligase PIAS4

Autor Lear, Travis, McKelvey, Alison C., Rajbhandari, Shristi, Dunn, Sarah R., Coon, Tiffany A., Connelly, William, Zhao, Joe Y., Kass, Daniel J., Zhang, Yingze, Liu, Yuan, Chen, Bill B.
Vydáno v J Exp Med (2016)

HIV Suppression Restores the Lung Mucosal CD4(+) T-Cell Viral Immune Response and Resolves CD8(+) T-Cell Alveolitis in Patients at Risk for HIV-Associated Chronic Obstructive Pulmo...

Autor Popescu, Iulia, Drummond, M. Bradley, Gama, Lucio, Lambert, Allison, Hoji, Aki, Coon, Tiffany, Merlo, Christian A., Wise, Robert A., Keruly, Jeanne, Clements, Janice E., Kirk, Gregory D., McDyer, John F.
Vydáno v J Infect Dis (2016)

Let-7d microRNA affects mesenchymal phenotypic properties of lung fibroblasts

Autor Huleihel, Luai, Ben-Yehudah, Ahmi, Milosevic, Jadranka, Yu, Guoying, Pandit, Kusum, Sakamoto, Koji, Yousef, Hanadie, LeJeune, Megan, Coon, Tiffany A., Redinger, Carrie J., Chensny, Lara, Manor, Ester, Schatten, Gerald, Kaminski, Naftali
Vydáno 2014

The proinflammatory role of HECTD2 in innate immunity and experimental lung injury

Autor Coon, Tiffany A., McKelvey, Alison C., Lear, Travis, Rajbhandari, Shristi, Dunn, Sarah R., Connelly, William, Zhao, Joe Y., Han, SeungHye, Liu, Yuan, Weathington, Nathaniel M., McVerry, Bryan J., Zhang, Yingze, Chen, Bill B.
Vydáno v Sci Transl Med (2015)