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Fbxl12 triggers G1 arrest by mediating degradation of calmodulin kinase I
Cell cycle progression through its regulatory control by changes in intracellular Ca(2+) levels at the G1/S transition mediates cellular proliferation and viability. Ca(2+)/CaM-dependent kinase 1 (CaMKI) appears critical in regulating the assembly of the cyclin D1/cdk4 complex essential for G1 progr...
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| Главные авторы: | , , , , , , , |
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| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2013
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3905573/ https://ncbi.nlm.nih.gov/pubmed/23707388 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2013.05.012 |
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