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Fbxl12 triggers G1 arrest by mediating degradation of calmodulin kinase I

Cell cycle progression through its regulatory control by changes in intracellular Ca(2+) levels at the G1/S transition mediates cellular proliferation and viability. Ca(2+)/CaM-dependent kinase 1 (CaMKI) appears critical in regulating the assembly of the cyclin D1/cdk4 complex essential for G1 progr...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Mallampalli, Rama K., Kaercher, Leah, Snavely, Courtney, Pulijala, Roopa, Chen, Bill B., Coon, Tiffany, Zhao, Jing, Agassandian, Marianna
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2013
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3905573/
https://ncbi.nlm.nih.gov/pubmed/23707388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2013.05.012
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