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Novel E3 ligase component FBXL7 ubiquitinates and degrades Aurora A, causing mitotic arrest
Aurora family kinases play pivotal roles in several steps during mitosis. Specifically, Aurora A kinase is an important regulator of bipolar mitotic spindle formation and chromosome segregation. Like other members of the Aurora family, Aurora A kinase is also regulated by post-translational modifica...
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| Główni autorzy: | , , , |
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| Format: | Artigo |
| Język: | Inglês |
| Wydane: |
Landes Bioscience
2012
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| Hasła przedmiotowe: | |
| Dostęp online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3318106/ https://ncbi.nlm.nih.gov/pubmed/22306998 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.4.19171 |
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