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F-box protein FBXL19–mediated ubiquitination and degradation of the receptor for IL-33 limits pulmonary inflammation

The ST2L receptor for interleukin 33 (IL-33) mediates pulmonary inflammation and immune system–related disorders, such as asthma and rheumatoid arthritis. At present, very little is known about the molecular regulation of ST2L expression. Here we found that FBXL19, an ‘orphan’ member of the Skp1–Cul...

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Detalhes bibliográficos
Main Authors: Zhao, Jing, Wei, Jianxin, Mialki, Rachel K, Mallampalli, Daniel F, Chen, Bill B, Coon, Tiffany, Zou, Chunbin, Mallampalli, Rama K, Zhao, Yutong
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643313/
https://ncbi.nlm.nih.gov/pubmed/22660580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2341
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