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Extracellular Signal-regulated Kinase (ERK) Regulates Cortactin Ubiquitination and Degradation in Lung Epithelial Cells

Cortactin, an actin-binding protein, is essential for cell growth and motility. We have shown that cortactin is regulated by reversible phosphorylation, but little is known regarding cortactin protein stability. Here, we show that lipopolysaccharide (LPS)-induced cortactin degradation is mediated by...

תיאור מלא

שמור ב:
מידע ביבליוגרפי
Main Authors: Zhao, Jing, Wei, Jianxin, Mialki, Rachel, Zou, Chunbin, Mallampalli, Rama K., Zhao, Yutong
פורמט: Artigo
שפה:Inglês
יצא לאור: American Society for Biochemistry and Molecular Biology 2012
נושאים:
גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC3365943/
https://ncbi.nlm.nih.gov/pubmed/22514278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.339507
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