Llwytho...

F-box protein FBXL19–mediated ubiquitination and degradation of the receptor for IL-33 limits pulmonary inflammation

The ST2L receptor for interleukin 33 (IL-33) mediates pulmonary inflammation and immune system–related disorders, such as asthma and rheumatoid arthritis. At present, very little is known about the molecular regulation of ST2L expression. Here we found that FBXL19, an ‘orphan’ member of the Skp1–Cul...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Zhao, Jing, Wei, Jianxin, Mialki, Rachel K, Mallampalli, Daniel F, Chen, Bill B, Coon, Tiffany, Zou, Chunbin, Mallampalli, Rama K, Zhao, Yutong
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2012
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3643313/
https://ncbi.nlm.nih.gov/pubmed/22660580
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ni.2341
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