Ubiquitin E3 ligase FIEL1 regulates fibrotic lung injury through SUMO-E3 ligase PIAS4

The E3 small ubiquitin-like modifier (SUMO) protein ligase protein inhibitor of activated STAT 4 (PIAS4) is a pivotal protein in regulating the TGFβ pathway. In this study, we discovered a new protein isoform encoded by KIAA0317, termed fibrosis-inducing E3 ligase 1 (FIEL1), which potently stimulate...

Popoln opis

Shranjeno v:
Bibliografske podrobnosti
izdano v:J Exp Med
Main Authors: Lear, Travis, McKelvey, Alison C., Rajbhandari, Shristi, Dunn, Sarah R., Coon, Tiffany A., Connelly, William, Zhao, Joe Y., Kass, Daniel J., Zhang, Yingze, Liu, Yuan, Chen, Bill B.
Format: Artigo
Jezik:Inglês
Izdano: The Rockefeller University Press 2016
Teme:
Research Articles
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886359/
https://ncbi.nlm.nih.gov/pubmed/27162139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1084/jem.20151229
Oznake: Označite
Brez oznak, prvi označite!

Podobne knjige/članki