Chemical Modification Patterns Compatible with High Potency Dicer-Substrate Small Interfering RNAs

Por Collingwood, Michael A., Rose, Scott D., Huang, Lingyan, Hillier, Chris, Amarzguioui, Mohammad, Wiiger, Merete T., Soifer, Harris S., Rossi, John J., Behlke, Mark A.
Publicado em 2008

A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs

Por Soifer, Harris S., Sano, Masayuki, Sakurai, Kumi, Chomchan, Pritsana, Sætrom, Pål, Sherman, Mark A., Collingwood, Michael A., Behlke, Mark A., Rossi, John J.
Publicado em 2008

Functional polarity is introduced by Dicer processing of short substrate RNAs

Por Rose, Scott D., Kim, Dong-Ho, Amarzguioui, Mohammed, Heidel, Jeremy D., Collingwood, Michael A., Davis, Mark E., Rossi, John J., Behlke, Mark A.
Publicado em 2005

Engineered AsCas12a Variants with Enhanced Activity and Broadened PAM Compatibility

Por Collingwood, Michael A., Vakulskas, Christopher A., Zhang, Liyang, Turk, Rolf, Bode, Nicole M., Jacobi, Ashley M., McNeill, Matthew S., McQuisten, Kyle, Thommandru, Bernice, Behlke, Mark A.
Publicado no J Biomol Tech (2019)

Simplified CRISPR tools for efficient genome editing and streamlined protocols for their delivery into mammalian cells and mouse zygotes

Por Jacobi, Ashley M., Rettig, Garrett R., Turk, Rolf, Collingwood, Michael A., Zeiner, Sarah A., Quadros, Rolen M., Harms, Donald W., Bonthuis, Paul J., Gregg, Christopher, Ohtsuka, Masato, Gurumurthy, Channabasavaiah B., Behlke, Mark A.
Publicado no Methods (2017)

Knockdown of β-catenin with Dicer-Substrate siRNAs Reduces Liver Tumor Burden In vivo

Por Dudek, Henryk, Wong, Darren H, Arvan, Rokhand, Shah, Anee, Wortham, Kathleen, Ying, Bo, Diwanji, Rohan, Zhou, Wei, Holmes, Benjamin, Yang, Hailin, Cyr, Wendy A, Zhou, Yi, Shah, Aalok, Farkiwala, Ruchir, Lee, Michael, Li, Yiting, Rettig, Garrett R, Collingwood, Michael A, Basu, Sujit K, Behlke, Mark A, Brown, Bob D
Publicado em 2014

Identification of preexisting adaptive immunity to Cas9 proteins in humans

Por Charlesworth, Carsten T., Deshpande, Priyanka S., Dever, Daniel P., Camarena, Joab, Lemgart, Viktor T., Cromer, M. Kyle, Vakulskas, Christopher A., Collingwood, Michael A., Zhang, Liyang, Bode, Nicole M., Behlke, Mark A., Dejene, Beruh, Cieniewicz, Brandon, Romano, Rosa, Lesch, Benjamin J., Gomez-Ospina, Natalia, Mantri, Sruthi, Pavel-Dinu, Mara, Weinberg, Kenneth I., Porteus, Matthew H.
Publicado no Nat Med (2019)

A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human haematopoietic stem and progenitor cells

Por Vakulskas, Christopher A., Dever, Daniel P., Rettig, Garrett R., Turk, Rolf, Jacobi, Ashley M., Collingwood, Michael A., Bode, Nicole M., McNeill, Matthew S., Yan, Shuqi, Camarena, Joab, Lee, Ciaran M., Park, So Hyun, Wiebking, Volker, Bak, Rasmus O., Gomez-Ospina, Natalia, Pavel-Dinu, Mara, Sun, Wenchao, Bao, Gang, Porteus, Matthew H., Behlke, Mark A.
Publicado no Nat Med (2018)