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A role for the Dicer helicase domain in the processing of thermodynamically unstable hairpin RNAs
In humans a single species of the RNAseIII enzyme Dicer processes both microRNA precursors into miRNAs and long double-stranded RNAs into small interfering RNAs (siRNAs). An interesting but poorly understood domain of the mammalian Dicer protein is the N-terminal helicase-like domain that possesses...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2582626/ https://ncbi.nlm.nih.gov/pubmed/18927112 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkn687 |
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