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Dicer-independent processing of short hairpin RNAs
Short hairpin RNAs (shRNAs) are widely used to induce RNA interference (RNAi). We tested a variety of shRNAs that differed in stem length and terminal loop size and revealed strikingly different RNAi activities and shRNA-processing patterns. Interestingly, we identified a specific shRNA design that...
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| Autori principali: | , , |
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| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Oxford University Press
2013
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3616727/ https://ncbi.nlm.nih.gov/pubmed/23376931 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkt036 |
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