Mechanistic insights on the Dicer-independent AGO2-mediated processing of AgoshRNAs

Short hairpin RNAs (shRNAs) are widely used for gene knockdown by inducing the RNA interference (RNAi) mechanism, both for research and therapeutic purposes. The shRNA precursor is processed by the RNase III-like enzyme Dicer into biologically active small interfering RNA (siRNA). This effector mole...

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Kaydedildi:
Detaylı Bibliyografya
Yayımlandı:RNA Biol
Asıl Yazarlar: Liu, Ying Poi, Karg, Margarete, Harwig, Alex, Herrera-Carrillo, Elena, Jongejan, Aldo, van Kampen, Antoine, Berkhout, Ben
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Taylor & Francis 2015
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615756/
https://ncbi.nlm.nih.gov/pubmed/25826416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1017204
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