Mechanistic insights on the Dicer-independent AGO2-mediated processing of AgoshRNAs

Short hairpin RNAs (shRNAs) are widely used for gene knockdown by inducing the RNA interference (RNAi) mechanism, both for research and therapeutic purposes. The shRNA precursor is processed by the RNase III-like enzyme Dicer into biologically active small interfering RNA (siRNA). This effector mole...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:RNA Biol
Egile Nagusiak: Liu, Ying Poi, Karg, Margarete, Harwig, Alex, Herrera-Carrillo, Elena, Jongejan, Aldo, van Kampen, Antoine, Berkhout, Ben
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Taylor & Francis 2015
Gaiak:
Research Paper
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4615756/
https://ncbi.nlm.nih.gov/pubmed/25826416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15476286.2015.1017204
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