Analysis of AgoshRNA maturation and loading into Ago2

The RNA interference (RNAi) pathway was recently expanded by the discovery of multiple alternative pathways for processing of natural microRNA (miRNA) and man-made short hairpin RNA (shRNA) molecules. One non-canonical pathway bypasses Dicer cleavage and requires instead processing by Argonaute2 (Ag...

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Udgivet i:PLoS One
Main Authors: Harwig, Alex, Kruize, Zita, Yang, Zhenhuang, Restle, Tobias, Berkhout, Ben
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5557517/
https://ncbi.nlm.nih.gov/pubmed/28809941
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0183269
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