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Design of extended short hairpin RNAs for HIV-1 inhibition

RNA interference (RNAi) targeted towards viral mRNAs is widely used to block virus replication in mammalian cells. The specific antiviral RNAi response can be induced via transfection of synthetic small interfering RNAs (siRNAs) or via intracellular expression of short hairpin RNAs (shRNAs). For HIV...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Ying Poi, Haasnoot, Joost, Berkhout, Ben
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2007
Schlagworte:
RNA
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2034457/
https://ncbi.nlm.nih.gov/pubmed/17715143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkm596
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