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Directed HIV-1 Evolution of Protease Inhibitor Resistance by Second-Generation Short Hairpin RNAs

Despite the success of antiretroviral drugs in decreasing AIDS-related mortality, a substantial fraction of HIV-infected patients experience therapy failure due to the emergence of drug-resistant virus variants. For durable inhibition of HIV-1 replication, the emergence of such escape viruses must b...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
मुख्य लेखकों: Schopman, Nick C. T., Braun, Anja, Berkhout, Ben
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: American Society for Microbiology 2012
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC3256055/
https://ncbi.nlm.nih.gov/pubmed/22064528
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05491-11
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