Priming Human Repopulating Hematopoietic Stem and Progenitor Cells for Cas9/sgRNA Gene Targeting

Por Charlesworth, Carsten T., Camarena, Joab, Cromer, M. Kyle, Vaidyanathan, Sriram, Bak, Rasmus O., Carte, Jason M., Potter, Jason, Dever, Daniel P., Porteus, Matthew H.
Publicado no Mol Ther Nucleic Acids (2018)

Global Transcriptional Response to CRISPR/Cas9-AAV6-Based Genome Editing in CD34(+) Hematopoietic Stem and Progenitor Cells

Por Cromer, M. Kyle, Vaidyanathan, Sriram, Ryan, Daniel E., Curry, Bo, Lucas, Anne Bergstrom, Camarena, Joab, Kaushik, Milan, Hay, Sarah R., Martin, Renata M., Steinfeld, Israel, Bak, Rasmus O., Dever, Daniel P., Hendel, Ayal, Bruhn, Laurakay, Porteus, Matthew H.
Publicado no Mol Ther (2018)

CRISPR/Cas9 Beta-globin Gene Targeting in Human Hematopoietic Stem Cells

Por Dever, Daniel P., Bak, Rasmus O., Reinisch, Andreas, Camarena, Joab, Washington, Gabriel, Nicolas, Carmencita E., Pavel-Dinu, Mara, Saxena, Nivi, Wilkens, Alec B., Mantri, Sruthi, Uchida, Nobuko, Hendel, Ayal, Narla, Anupama, Majeti, Ravindra, Weinberg, Kenneth I., Porteus, Matthew H.
Publicado no Nature (2016)

CRISPR/Cas9 Genome Engineering in Engraftable Human Brain-Derived Neural Stem Cells

Por Dever, Daniel P., Scharenberg, Samantha G., Camarena, Joab, Kildebeck, Eric J., Clark, Joseph T., Martin, Renata M., Bak, Rasmus O., Tang, Yuming, Dohse, Monika, Birgmeier, Johannes A., Jagadeesh, Karthik A., Bejerano, Gill, Tsukamoto, Ann, Gomez-Ospina, Natalia, Uchida, Nobuko, Porteus, Matthew H.
Publicado no iScience (2019)

A high-fidelity Cas9 mutant delivered as a ribonucleoprotein complex enables efficient gene editing in human haematopoietic stem and progenitor cells

Por Vakulskas, Christopher A., Dever, Daniel P., Rettig, Garrett R., Turk, Rolf, Jacobi, Ashley M., Collingwood, Michael A., Bode, Nicole M., McNeill, Matthew S., Yan, Shuqi, Camarena, Joab, Lee, Ciaran M., Park, So Hyun, Wiebking, Volker, Bak, Rasmus O., Gomez-Ospina, Natalia, Pavel-Dinu, Mara, Sun, Wenchao, Bao, Gang, Porteus, Matthew H., Behlke, Mark A.
Publicado no Nat Med (2018)