Global Transcriptional Response to CRISPR/Cas9-AAV6-Based Genome Editing in CD34(+) Hematopoietic Stem and Progenitor Cells

Genome-editing technologies are currently being translated to the clinic. However, cellular effects of the editing machinery have yet to be fully elucidated. Here, we performed global microarray-based gene expression measurements on human CD34(+) hematopoietic stem and progenitor cells that underwen...

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發表在:Mol Ther
Main Authors: Cromer, M. Kyle, Vaidyanathan, Sriram, Ryan, Daniel E., Curry, Bo, Lucas, Anne Bergstrom, Camarena, Joab, Kaushik, Milan, Hay, Sarah R., Martin, Renata M., Steinfeld, Israel, Bak, Rasmus O., Dever, Daniel P., Hendel, Ayal, Bruhn, Laurakay, Porteus, Matthew H.
格式: Artigo
語言:Inglês
出版: American Society of Gene & Cell Therapy 2018
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Original Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171165/
https://ncbi.nlm.nih.gov/pubmed/30005866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.06.002
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