Global Transcriptional Response to CRISPR/Cas9-AAV6-Based Genome Editing in CD34(+) Hematopoietic Stem and Progenitor Cells

Genome-editing technologies are currently being translated to the clinic. However, cellular effects of the editing machinery have yet to be fully elucidated. Here, we performed global microarray-based gene expression measurements on human CD34(+) hematopoietic stem and progenitor cells that underwen...

Πλήρης περιγραφή

Αποθηκεύτηκε σε:
Λεπτομέρειες βιβλιογραφικής εγγραφής
Τόπος έκδοσης:Mol Ther
Κύριοι συγγραφείς: Cromer, M. Kyle, Vaidyanathan, Sriram, Ryan, Daniel E., Curry, Bo, Lucas, Anne Bergstrom, Camarena, Joab, Kaushik, Milan, Hay, Sarah R., Martin, Renata M., Steinfeld, Israel, Bak, Rasmus O., Dever, Daniel P., Hendel, Ayal, Bruhn, Laurakay, Porteus, Matthew H.
Μορφή: Artigo
Γλώσσα:Inglês
Έκδοση: American Society of Gene & Cell Therapy 2018
Θέματα:
Original Article
Διαθέσιμο Online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6171165/
https://ncbi.nlm.nih.gov/pubmed/30005866
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ymthe.2018.06.002
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