The Therapeutic Potential of Cystathionine β-Synthetase/Hydrogen Sulfide Inhibition in Cancer

Por Hellmich, Mark R., Coletta, Ciro, Chao, Celia, Szabo, Csaba
Publicado no Antioxid Redox Signal (2015)

Regulation of Mitochondrial Poly(ADP-Ribose) Polymerase Activation by the β-Adrenoceptor/cAMP/Protein Kinase A Axis during Oxidative Stress

Por Brunyanszki, Attila, Olah, Gabor, Coletta, Ciro, Szczesny, Bartosz, Szabo, Csaba
Publicado em 2014

Cell-Based Screening Identifies Paroxetine as an Inhibitor of Diabetic Endothelial Dysfunction

Por Gerö, Domokos, Szoleczky, Petra, Suzuki, Kunihiro, Módis, Katalin, Oláh, Gabor, Coletta, Ciro, Szabo, Csaba
Publicado em 2013

Tumor-derived hydrogen sulfide, produced by cystathionine-β-synthase, stimulates bioenergetics, cell proliferation, and angiogenesis in colon cancer

Por Szabo, Csaba, Coletta, Ciro, Chao, Celia, Módis, Katalin, Szczesny, Bartosz, Papapetropoulos, Andreas, Hellmich, Mark R.
Publicado em 2013

Effect of S-adenosyl-L-methionine (SAM), an allosteric activator of cystathionine-β-synthase (CBS) on colorectal cancer cell proliferation and bioenergetics in vitro

Por Módis, Katalin, Coletta, Ciro, Asimakopoulou, Antonia, Szczesny, Bartosz, Chao, Celia, Papapetropoulos, Andreas, Hellmich, Mark R., Szabo, Csaba
Publicado em 2014

Endothelial dysfunction is a potential contributor to multiple organ failure and mortality in aged mice subjected to septic shock: preclinical studies in a murine model of cecal li...

Por Coletta, Ciro, Módis, Katalin, Oláh, Gábor, Brunyánszki, Attila, Herzig, Daniela S, Sherwood, Edward R, Ungvári, Zoltán, Szabo, Csaba
Publicado em 2014

Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part I. Biochemical and physiological mechanisms

Por Szabo, Csaba, Ransy, Céline, Módis, Katalin, Andriamihaja, Mireille, Murghes, Baptiste, Coletta, Ciro, Olah, Gabor, Yanagi, Kazunori, Bouillaud, Frédéric
Publicado em 2014

AP39 [10-oxo-10-(4-(3-thioxo-3H-1,2-dithiol-5yl)phenoxy)decyl) triphenylphosphonium bromide], a mitochondrially targeted hydrogen sulfide donor, stimulates cellular bioenergetics,...

Por Szczesny, Bartosz, Módis, Katalin, Yanagi, Kazunori, Coletta, Ciro, Le Trionnaire, Sophie, Wood, Mark E., Whiteman, Matthew, Szabo, Csaba
Publicado no Nitric Oxide (2014)

Adenosine and inosine exert cytoprotective effects in an in vitro model of liver ischemia-reperfusion injury

Por MÓDIS, KATALIN, GERŐ, DOMOKOS, STANGL, RITA, ROSERO, OLIVÉR, SZIJÁRTÓ, ATTILA, LOTZ, GÁBOR, MOHÁCSIK, PETRA, SZOLECZKY, PETRA, COLETTA, CIRO, SZABÓ, CSABA
Publicado em 2013

Hydrogen Sulfide Contributes to Retinal Neovascularization in Ischemia-Induced Retinopathy

Por Gersztenkorn, David, Coletta, Ciro, Zhu, Shuang, Ha, Yonju, Liu, Hua, Tie, Hongyan, Zhou, Jia, Szabo, Csaba, Zhang, Wenbo, Motamedi, Massoud
Publicado no Invest Ophthalmol Vis Sci (2016)

Selectivity of commonly used pharmacological inhibitors for cystathionine β synthase (CBS) and cystathionine γ lyase (CSE)

Por Asimakopoulou, Antonia, Panopoulos, Panagiotis, Chasapis, Christos T, Coletta, Ciro, Zhou, Zongmin, Cirino, Giuseppe, Giannis, Athanassios, Szabo, Csaba, Spyroulias, Georgios A, Papapetropoulos, Andreas
Publicado em 2013

Regulation of Vascular Tone, Angiogenesis and Cellular Bioenergetics by the 3-Mercaptopyruvate Sulfurtransferase/H(2)S Pathway: Functional Impairment by Hyperglycemia and Restorati...

Por Coletta, Ciro, Módis, Katalin, Szczesny, Bartosz, Brunyánszki, Attila, Oláh, Gábor, Rios, Ester CS, Yanagi, Kazunori, Ahmad, Akbar, Papapetropoulos, Andreas, Szabo, Csaba
Publicado no Mol Med (2015)

Hydrogen sulfide and nitric oxide are mutually dependent in the regulation of angiogenesis and endothelium-dependent vasorelaxation

Por Coletta, Ciro, Papapetropoulos, Andreas, Erdelyi, Katalin, Olah, Gabor, Módis, Katalin, Panopoulos, Panagiotis, Asimakopoulou, Antonia, Gerö, Domokos, Sharina, Iraida, Martin, Emil, Szabo, Csaba
Publicado em 2012

Hydrogen sulphide induces mouse paw oedema through activation of phospholipase A(2)

Por di Villa Bianca, Roberta d'Emmanuele, Coletta, Ciro, Mitidieri, Emma, De Dominicis, Gianfranco, Rossi, Antonietta, Sautebin, Lidia, Cirino, Giuseppe, Bucci, Mariarosaria, Sorrentino, Raffaella
Publicado em 2010

Regulation of mitochondrial bioenergetic function by hydrogen sulfide. Part II. Pathophysiological and therapeutic aspects

Por Módis, Katalin, Bos, Eelke M, Calzia, Enrico, van Goor, Harry, Coletta, Ciro, Papapetropoulos, Andreas, Hellmich, Mark R, Radermacher, Peter, Bouillaud, Frédéric, Szabo, Csaba
Publicado em 2014

Role of Hydrogen Sulfide in Paramyxovirus Infections

Por Li, Hui, Ma, Yinghong, Escaffre, Oliver, Ivanciuc, Teodora, Komaravelli, Narayana, Kelley, John P., Coletta, Ciro, Szabo, Csaba, Rockx, Barry, Garofalo, Roberto P., Casola, Antonella
Publicado no J Virol (2015)

Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function

Por Suzuki, Kunihiro, Olah, Gabor, Modis, Katalin, Coletta, Ciro, Kulp, Gabriella, Gerö, Domokos, Szoleczky, Petra, Chang, Tuanjie, Zhou, Zongmin, Wu, Lingyun, Wang, Rui, Papapetropoulos, Andreas, Szabo, Csaba
Publicado em 2011

Cardioprotection by H(2)S engages a cGMP-dependent protein kinase G/phospholamban pathway

Por Bibli, Sofia-Iris, Andreadou, Ioanna, Chatzianastasiou, Athanasia, Tzimas, Christos, Sanoudou, Despina, Kranias, Evangelia, Brouckaert, Peter, Coletta, Ciro, Szabo, Csaba, Kremastinos, Dimitrios Th., Iliodromitis, Efstathios K., Papapetropoulos, Andreas
Publicado no Cardiovasc Res (2015)

Immunomodulatory and Antibacterial Effects of Cystatin 9 against Francisella tularensis

Por Eaves-Pyles, Tonyia, Patel, Jignesh, Arigi, Emma, Cong, Yingzi, Cao, Anthony, Garg, Nisha, Dhiman, Monisha, Pyles, Richard B, Arulanandam, Bernard, Miller, Aaron L, Popov, Vsevolod L, Soong, Lynn, Carlsen, Eric D, Coletta, Ciro, Szabo, Csaba, Almeida, Igor C.
Publicado em 2013

Cystathionine-β-Synthase Inhibition for Colon Cancer: Enhancement of the Efficacy of Aminooxyacetic Acid via the Prodrug Approach

Por Chao, Celia, Zatarain, John R, Ding, Ye, Coletta, Ciro, Mrazek, Amy A, Druzhyna, Nadiya, Johnson, Paul, Chen, Haiying, Hellmich, Judy L, Asimakopoulou, Antonia, Yanagi, Kazunori, Olah, Gabor, Szoleczky, Petra, Törö, Gabor, Bohanon, Fredrick J, Cheema, Minal, Lewis, Rachel, Eckelbarger, David, Ahmad, Akbar, Módis, Katalin, Untereiner, Ashley, Szczesny, Bartosz, Papapetropoulos, Andreas, Zhou, Jia, Hellmich, Mark R, Szabo, Csaba
Publicado no Mol Med (2016)