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Effect of S-adenosyl-L-methionine (SAM), an allosteric activator of cystathionine-β-synthase (CBS) on colorectal cancer cell proliferation and bioenergetics in vitro

Recent data show that colon cancer cells selectively overexpress cystathionine-β-synthase (CBS), which produces hydrogen sulfide (H(2)S), to maintain cellular bioenergetics, support tumor growth and stimulate angiogenesis and vasorelaxation in the tumor microenvironment. The purpose of the current s...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Päätekijät: Módis, Katalin, Coletta, Ciro, Asimakopoulou, Antonia, Szczesny, Bartosz, Chao, Celia, Papapetropoulos, Andreas, Hellmich, Mark R., Szabo, Csaba
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2014
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4156891/
https://ncbi.nlm.nih.gov/pubmed/24667534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.niox.2014.03.001
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