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Cell-Based Screening Identifies Paroxetine as an Inhibitor of Diabetic Endothelial Dysfunction
We have conducted a phenotypic screening in endothelial cells exposed to elevated extracellular glucose (an in vitro model of hyperglycemia) to identify compounds that prevent hyperglycemia-induced reactive oxygen species (ROS) formation without adversely affecting cell viability. From a focused lib...
Tallennettuna:
| Päätekijät: | , , , , , , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
American Diabetes Association
2013
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3581231/ https://ncbi.nlm.nih.gov/pubmed/23223176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0789 |
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