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Hydrogen sulfide replacement therapy protects the vascular endothelium in hyperglycemia by preserving mitochondrial function

The goal of the present studies was to investigate the role of changes in hydrogen sulfide (H(2)S) homeostasis in the pathogenesis of hyperglycemic endothelial dysfunction. Exposure of bEnd3 microvascular endothelial cells to elevated extracellular glucose (in vitro “hyperglycemia”) induced the mito...

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Detalles Bibliográficos
Autores principales: Suzuki, Kunihiro, Olah, Gabor, Modis, Katalin, Coletta, Ciro, Kulp, Gabriella, Gerö, Domokos, Szoleczky, Petra, Chang, Tuanjie, Zhou, Zongmin, Wu, Lingyun, Wang, Rui, Papapetropoulos, Andreas, Szabo, Csaba
Formato: Artigo
Lenguaje:Inglês
Publicado: National Academy of Sciences 2011
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC3158211/
https://ncbi.nlm.nih.gov/pubmed/21808008
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1105121108
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