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Cell-Based Screening Identifies Paroxetine as an Inhibitor of Diabetic Endothelial Dysfunction
We have conducted a phenotypic screening in endothelial cells exposed to elevated extracellular glucose (an in vitro model of hyperglycemia) to identify compounds that prevent hyperglycemia-induced reactive oxygen species (ROS) formation without adversely affecting cell viability. From a focused lib...
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| 主要な著者: | , , , , , , |
|---|---|
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
American Diabetes Association
2013
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3581231/ https://ncbi.nlm.nih.gov/pubmed/23223176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db12-0789 |
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