Role of Base Excision “Repair” Enzymes in Erasing Epigenetic Marks from DNA

par Drohat, Alexander C., Coey, Christopher T.
Publié dans Chem Rev (2016)

Kinetic Methods for Studying DNA Glycosylases Functioning in Base Excision Repair

par Coey, Christopher T., Drohat, Alexander C.
Publié dans Methods Enzymol (2017)

Defining the impact of sumoylation on substrate binding and catalysis by thymine DNA glycosylase

par Coey, Christopher T, Drohat, Alexander C
Publié dans Nucleic Acids Res (2018)

Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA

par Malik, Shuja S., Coey, Christopher T., Varney, Kristen M., Pozharski, Edwin, Drohat, Alexander C.
Publié dans Nucleic Acids Res (2015)

Characterizing Requirements for Small Ubiquitin-like Modifier (SUMO) Modification and Binding on Base Excision Repair Activity of Thymine-DNA Glycosylase in Vivo

par McLaughlin, Dylan, Coey, Christopher T., Yang, Wei-Chih, Drohat, Alexander C., Matunis, Michael J.
Publié dans J Biol Chem (2016)

Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues

par Coey, Christopher T., Malik, Shuja S., Pidugu, Lakshmi S., Varney, Kristen M., Pozharski, Edwin, Drohat, Alexander C.
Publié dans Nucleic Acids Res (2016)

Structural basis for excision of 5-formylcytosine by thymine DNA glycosylase

par Pidugu, Lakshmi S., Flowers, Joshua W., Coey, Christopher T., Pozharski, Edwin, Greenberg, Marc M., Drohat, Alexander C.
Publié dans Biochemistry (2016)

E2-mediated Small Ubiquitin-like Modifier (SUMO) Modification of Thymine DNA Glycosylase Is Efficient but Not Selective for the Enzyme-Product Complex

par Coey, Christopher T., Fitzgerald, Megan E., Maiti, Atanu, Reiter, Katherine H., Guzzo, Catherine M., Matunis, Michael J., Drohat, Alexander C.
Publié 2014