Role of Base Excision “Repair” Enzymes in Erasing Epigenetic Marks from DNA

Por Drohat, Alexander C., Coey, Christopher T.
Publicado no Chem Rev (2016)

Kinetic Methods for Studying DNA Glycosylases Functioning in Base Excision Repair

Por Coey, Christopher T., Drohat, Alexander C.
Publicado no Methods Enzymol (2017)

Defining the impact of sumoylation on substrate binding and catalysis by thymine DNA glycosylase

Por Coey, Christopher T, Drohat, Alexander C
Publicado no Nucleic Acids Res (2018)

Thymine DNA glycosylase exhibits negligible affinity for nucleobases that it removes from DNA

Por Malik, Shuja S., Coey, Christopher T., Varney, Kristen M., Pozharski, Edwin, Drohat, Alexander C.
Publicado no Nucleic Acids Res (2015)

Characterizing Requirements for Small Ubiquitin-like Modifier (SUMO) Modification and Binding on Base Excision Repair Activity of Thymine-DNA Glycosylase in Vivo

Por McLaughlin, Dylan, Coey, Christopher T., Yang, Wei-Chih, Drohat, Alexander C., Matunis, Michael J.
Publicado no J Biol Chem (2016)

Structural basis of damage recognition by thymine DNA glycosylase: Key roles for N-terminal residues

Por Coey, Christopher T., Malik, Shuja S., Pidugu, Lakshmi S., Varney, Kristen M., Pozharski, Edwin, Drohat, Alexander C.
Publicado no Nucleic Acids Res (2016)

Structural basis for excision of 5-formylcytosine by thymine DNA glycosylase

Por Pidugu, Lakshmi S., Flowers, Joshua W., Coey, Christopher T., Pozharski, Edwin, Greenberg, Marc M., Drohat, Alexander C.
Publicado no Biochemistry (2016)

E2-mediated Small Ubiquitin-like Modifier (SUMO) Modification of Thymine DNA Glycosylase Is Efficient but Not Selective for the Enzyme-Product Complex

Por Coey, Christopher T., Fitzgerald, Megan E., Maiti, Atanu, Reiter, Katherine H., Guzzo, Catherine M., Matunis, Michael J., Drohat, Alexander C.
Publicado em 2014