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Role of Base Excision “Repair” Enzymes in Erasing Epigenetic Marks from DNA

Base excision repair (BER) is one of several DNA repair pathways found in all three domains of life. BER counters the mutagenic and cytotoxic effects of damage that occurs continuously to the nitrogenous bases in DNA, and its critical role in maintaining genomic integrity is well established. Howeve...

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Detalhes bibliográficos
Publicado no:Chem Rev
Main Authors: Drohat, Alexander C., Coey, Christopher T.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299066/
https://ncbi.nlm.nih.gov/pubmed/27501078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.6b00191
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