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Role of Base Excision “Repair” Enzymes in Erasing Epigenetic Marks from DNA

Base excision repair (BER) is one of several DNA repair pathways found in all three domains of life. BER counters the mutagenic and cytotoxic effects of damage that occurs continuously to the nitrogenous bases in DNA, and its critical role in maintaining genomic integrity is well established. Howeve...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Chem Rev
Prif Awduron: Drohat, Alexander C., Coey, Christopher T.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5299066/
https://ncbi.nlm.nih.gov/pubmed/27501078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.chemrev.6b00191
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