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Role of base excision repair in maintaining the genetic and epigenetic integrity of CpG sites
Cytosine methylation at CpG dinucleotides is a central component of epigenetic regulation in vertebrates, and the base excision repair (BER) pathway is important for maintaining both the genetic stability and the methylation status of CpG sites. This perspective focuses on two enzymes that are of pa...
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| Publicado no: | DNA Repair (Amst) |
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| Main Authors: | , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4903958/ https://ncbi.nlm.nih.gov/pubmed/26021671 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2015.04.011 |
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