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Human DNA mismatch repair in vitro operates independently of methylation status at CpG sites

Whereas in Escherichia coli DNA mismatch repair is directed to the newly synthesized strand due to its transient lack of adenine methylation, the molecular determinants of strand discrimination in eukaryotes are presently unknown. In mammalian cells, cytosine methylation within CpG sites may represe...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Principais autores: Drummond, James T., Bellacosa, Alfonso
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2001
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC55720/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/11376141/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/29.11.2234
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