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TET-TDG active DNA demethylation at CpG and non-CpG sites
In mammalian genomes, cytosine methylation occurs predominantly at CG (or CpG) dinucleotide contexts. As part of dynamic epigenetic regulation, 5-methylcytosine (mC) can be erased by active DNA demethylation, whereby ten-eleven translocation (TET) enzymes catalyze the stepwise oxidation of mC to 5-h...
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| Vydáno v: | J Mol Biol |
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| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2021
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC8005466/ https://ncbi.nlm.nih.gov/pubmed/33561435 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2021.166877 |
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