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TET enzymes, TDG and the dynamics of DNA demethylation

DNA methylation has a profound impact on genome stability, transcription and development. Although enzymes that catalyse DNA methylation have been well characterized, those that are involved in methyl group removal have remained elusive, until recently. The transformative discovery that ten-eleven t...

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Detalles Bibliográficos
Main Authors: Kohli, Rahul M., Zhang, Yi
Formato: Artigo
Idioma:Inglês
Publicado: 2013
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046508/
https://ncbi.nlm.nih.gov/pubmed/24153300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12750
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