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TET enzymes, TDG and the dynamics of DNA demethylation

DNA methylation has a profound impact on genome stability, transcription and development. Although enzymes that catalyse DNA methylation have been well characterized, those that are involved in methyl group removal have remained elusive, until recently. The transformative discovery that ten-eleven t...

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Détails bibliographiques
Auteurs principaux: Kohli, Rahul M., Zhang, Yi
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4046508/
https://ncbi.nlm.nih.gov/pubmed/24153300
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12750
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