Genetics of Systemic Sclerosis: An Update

Por Broen, Jasper C. A., Coenen, Marieke J. H., Radstake, Timothy R. D. J.
Publicado em 2011

Dutch myotonic dystrophy type 2 patients and a North-African DM2 family carry the common European founder haplotype

Por Coenen, Marieke J H, Tieleman, Alide A, Schijvenaars, Mascha M V A P, Leferink, Maike, Ranum, Laura P W, Scheffer, Hans, van Engelen, Baziel G M
Publicado em 2011

A Replication Study of the Association between Rheumatoid Arthritis and Deletion of the Late Cornified Envelope Genes LCE3B and LCE3C

Por Bergboer, Judith G. M., Umićević-Mirkov, Maša, Fransen, Jaap, den Heijer, Martin, Franke, Barbara, van Riel, Piet L. C. M., Schalkwijk, Joost, Coenen, Marieke J. H.
Publicado em 2012

Macrophage migration inhibitory factor polymorphisms do not predict therapeutic response to glucocorticoids or to tumour necrosis factor α‐neutralising treatments in rheumatoid art...

Por Radstake, Timothy R D J, Fransen, Jaap, Toonen, Erik J M, Coenen, Marieke J H, Eijsbouts, Agnes E, Donn, Rachelle, van den Hoogen, Frank H J, van Riel, Piet L C M
Publicado em 2007

TRPC6 Single Nucleotide Polymorphisms and Progression of Idiopathic Membranous Nephropathy

Por Hofstra, Julia M., Coenen, Marieke J. H., Schijvenaars, Mascha M. V. A. P., Berden, Jo H. M., van der Vlag, Johan, Hoefsloot, Lies H., Knoers, Nine V. A. M., Wetzels, Jack F. M., Nijenhuis, Tom
Publicado em 2014

Influence of Genetic Variants in TPMT and COMT Associated with Cisplatin Induced Hearing Loss in Patients with Cancer: Two New Cohorts and a Meta-Analysis Reveal Significant Hetero...

Por Hagleitner, Melanie M., Coenen, Marieke J. H., Patino-Garcia, Ana, de Bont, Eveline S. J. M., Gonzalez-Neira, Anna, Vos, Hanneke I., van Leeuwen, Frank N., Gelderblom, Hans, Hoogerbrugge, Peter M., Guchelaar, Henk-Jan, te Loo, Maroeska W. M.
Publicado no PLoS One (2014)

Validation Study of Existing Gene Expression Signatures for Anti-TNF Treatment in Patients with Rheumatoid Arthritis

Por Toonen, Erik J. M., Gilissen, Christian, Franke, Barbara, Kievit, Wietske, Eijsbouts, Agnes M., den Broeder, Alfons A., van Reijmersdal, Simon V., Veltman, Joris A., Scheffer, Hans, Radstake, Timothy R. D. J., van Riel, Piet L. C. M., Barrera, Pilar, Coenen, Marieke J. H.
Publicado em 2012

Phospholipase A2 Receptor (PLA2R1) Sequence Variants in Idiopathic Membranous Nephropathy

Por Coenen, Marieke J.H., Hofstra, Julia M., Debiec, Hanna, Stanescu, Horia C., Medlar, Alan J., Stengel, Bénédicte, Boland-Augé, Anne, Groothuismink, Johanne M., Bockenhauer, Detlef, Powis, Steve H., Mathieson, Peter W., Brenchley, Paul E., Kleta, Robert, Wetzels, Jack F.M., Ronco, Pierre
Publicado em 2013

IL-32 promoter SNP rs4786370 predisposes to modified lipoprotein profiles in patients with rheumatoid arthritis

Por Damen, Michelle S. M. A., Agca, Rabia, Holewijn, Suzanne, de Graaf, Jacqueline, Dos Santos, Jéssica C., van Riel, Piet L., Fransen, Jaap, Coenen, Marieke J. H., Nurmohamed, Mike T., Netea, Mihai G., Dinarello, Charles A., Joosten, Leo A. B., Heinhuis, Bas, Popa, Calin D.
Publicado no Sci Rep (2017)

More Dose-dependent Side Effects with Mercaptopurine over Azathioprine in IBD Treatment Due to Relatively Higher Dosing

Por Broekman, Mark M. T. J., Coenen, Marieke J. H., van Marrewijk, Corine J., Wanten, Geert J. A., Wong, Dennis R., Verbeek, Andre L. M., Klungel, Olaf H., Hooymans, Piet M., Guchelaar, Henk-Jan, Scheffer, Hans, Derijks, Luc J. J., de Jong, Dirk J.
Publicado no Inflamm Bowel Dis (2017)

Novel Association in Chromosome 4q27 Region with Rheumatoid Arthritis and Confirmation of Type 1 Diabetes Point to a General Risk Locus for Autoimmune Diseases

Por Zhernakova, Alexandra , Alizadeh, Behrooz Z. , Bevova, Marianna , Leeuwen, Miek A. van , Coenen, Marieke J. H. , Franke, Barbara , Franke, Lude , Posthumus, Marcel D. , Heel, David A. van , Steege, Gerrit van der , Radstake, Timothy R. D. J. , Barrera, Pilar , Roep, Bart O. , Koeleman, Bobby P. C. , Wijmenga, Cisca 
Publicado em 2007

Patients’ beliefs about medicine are associated with early thiopurine discontinuation in patients with inflammatory bowel diseases

Por Broekman, Mark M.T.J., Coenen, Marieke J.H., Wanten, Geert J., van Marrewijk, Corine J., Kievit, Wietske, Klungel, Olaf H., Verbeek, André L.M., Wong, Dennis R., Hooymans, Piet M., Guchelaar, Henk-Jan, Scheffer, Hans, Derijks, Luc J.J., Bouvy, Marcel L., de Jong, Dirk J.
Publicado no Eur J Gastroenterol Hepatol (2018)

Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge

Por Plenge, Robert M., Greenberg, Jeffrey D., Mangravite, Lara M., Derry, Jonathan M. J., Stahl, Eli A., Coenen, Marieke J. H., Barton, Anne, Padyukov, Leonid, Klareskog, Lars, Gregersen, Peter K., Mariette, Xavier, Moreland, Larry W., Bridges, S Louis, de Vries, Niek, Huizinga, Tom W. J., Guchelaar, Henk-Jan, Friend, Stephen H., Stolovitzky, Gustavo
Publicado em 2013

Genetic Variants in Toll-Like Receptors Are Not Associated with Rheumatoid Arthritis Susceptibility or Anti-Tumour Necrosis Factor Treatment Outcome

Por Coenen, Marieke J. H., Enevold, Christian, Barrera, Pilar, Schijvenaars, Mascha M. V. A. P., Toonen, Erik J. M., Scheffer, Hans, Padyukov, Leonid, Kastbom, Alf, Klareskog, Lars, Barton, Anne, Kievit, Wietske, Rood, Maarten J., Jansen, Tim L., Swinkels, Dorine, van Riel, Piet L. C. M., Franke, Barbara, Bendtzen, Klaus, Radstake, Timothy R. D. J.
Publicado em 2010

CSK regulatory polymorphism is associated with systemic lupus erythematosus and influences B cell signaling and activation

Por Manjarrez-Orduño, Nataly, Marasco, Emiliano, Chung, Sharon A., Katz, Matthew S., Kiridly, Jenna F., Simpfendorfer, Kim R., Freudenberg, Jan, Ballard, David H., Nashi, Emil, Hopkins, Thomas J., Graham, Deborah S Cunninghame, Lee, Annette T., Coenen, Marieke J. H., Franke, Barbara, Swinkels, Dorine W., Graham, Robert R., Kimberly, Robert P., Gaffney, Patrick M., Vyse, Timothy J., Behrens, Timothy W., Criswell, Lindsey A., Diamond, Betty, Gregersen, Peter K.
Publicado em 2012

Association of variation in Fcγ receptor 3B gene copy number with rheumatoid arthritis in Caucasian samples

Por McKinney, Cushla, Fanciulli, Manuela, Merriman, Marilyn E, Phipps-Green, Amanda, Alizadeh, Behrooz Z, Koeleman, Bobby P C, Dalbeth, Nicola, Gow, Peter J, Harrison, Andrew A, Highton, John, Jones, Peter B, Stamp, Lisa K, Steer, Sophia, Barrera, Pilar, Coenen, Marieke J H, Franke, Barbara, van Riel, Piet L C M, Vyse, Tim J, Aitman, Tim J, Radstake, Timothy R D J, Merriman, Tony R
Publicado em 2010

Meta-Analysis of Genome-Wide Association Studies in Celiac Disease and Rheumatoid Arthritis Identifies Fourteen Non-HLA Shared Loci

Por Zhernakova, Alexandra, Stahl, Eli A., Trynka, Gosia, Raychaudhuri, Soumya, Festen, Eleanora A., Franke, Lude, Westra, Harm-Jan, Fehrmann, Rudolf S. N., Kurreeman, Fina A. S., Thomson, Brian, Gupta, Namrata, Romanos, Jihane, McManus, Ross, Ryan, Anthony W., Turner, Graham, Brouwer, Elisabeth, Posthumus, Marcel D., Remmers, Elaine F., Tucci, Francesca, Toes, Rene, Grandone, Elvira, Mazzilli, Maria Cristina, Rybak, Anna, Cukrowska, Bozena, Coenen, Marieke J. H., Radstake, Timothy R. D. J., van Riel, Piet L. C. M., Li, Yonghong, de Bakker, Paul I. W., Gregersen, Peter K., Worthington, Jane, Siminovitch, Katherine A., Klareskog, Lars, Huizinga, Tom W. J., Wijmenga, Cisca, Plenge, Robert M.
Publicado em 2011

A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations

Por Bossini-Castillo, Lara, Martin, Jose-Ezequiel, Broen, Jasper, Gorlova, Olga, Simeón, Carmen P., Beretta, Lorenzo, Vonk, Madelon C., Luis Callejas, Jose, Castellví, Ivan, Carreira, Patricia, José García-Hernández, Francisco, Fernández Castro, Mónica, Coenen, Marieke J.H., Riemekasten, Gabriela, Witte, Torsten, Hunzelmann, Nicolas, Kreuter, Alexander, Distler, Jörg H.W., Koeleman, Bobby P., Voskuyl, Alexandre E., Schuerwegh, Annemie J., Palm, Øyvind, Hesselstrand, Roger, Nordin, Annika, Airó, Paolo, Lunardi, Claudio, Scorza, Raffaella, Shiels, Paul, van Laar, Jacob M., Herrick, Ariane, Worthington, Jane, Denton, Christopher, Tan, Filemon K., Arnett, Frank C., Agarwal, Sandeep K., Assassi, Shervin, Fonseca, Carmen, Mayes, Maureen D., Radstake, Timothy R.D.J., Martin, Javier
Publicado em 2012

Integration of Sequence Data from a Consanguineous Family with Genetic Data from an Outbred Population Identifies PLB1 as a Candidate Rheumatoid Arthritis Risk Gene

Por Okada, Yukinori, Diogo, Dorothee, Greenberg, Jeffrey D., Mouassess, Faten, Achkar, Walid A. L., Fulton, Robert S., Denny, Joshua C., Gupta, Namrata, Mirel, Daniel, Gabriel, Stacy, Li, Gang, Kremer, Joel M., Pappas, Dimitrios A., Carroll, Robert J., Eyler, Anne E., Trynka, Gosia, Stahl, Eli A., Cui, Jing, Saxena, Richa, Coenen, Marieke J. H., Guchelaar, Henk-Jan, Huizinga, Tom W. J., Dieudé, Philippe, Mariette, Xavier, Barton, Anne, Canhão, Helena, Fonseca, João E., de Vries, Niek, Tak, Paul P., Moreland, Larry W., Bridges, S. Louis, Miceli-Richard, Corinne, Choi, Hyon K., Kamatani, Yoichiro, Galan, Pilar, Lathrop, Mark, Raj, Towfique, De Jager, Philip L., Raychaudhuri, Soumya, Worthington, Jane, Padyukov, Leonid, Klareskog, Lars, Siminovitch, Katherine A., Gregersen, Peter K., Mardis, Elaine R., Arayssi, Thurayya, Kazkaz, Layla A., Plenge, Robert M.
Publicado em 2014

TYK2 Protein-Coding Variants Protect against Rheumatoid Arthritis and Autoimmunity, with No Evidence of Major Pleiotropic Effects on Non-Autoimmune Complex Traits

Por Diogo, Dorothée, Bastarache, Lisa, Liao, Katherine P., Graham, Robert R., Fulton, Robert S., Greenberg, Jeffrey D., Eyre, Steve, Bowes, John, Cui, Jing, Lee, Annette, Pappas, Dimitrios A., Kremer, Joel M., Barton, Anne, Coenen, Marieke J. H., Franke, Barbara, Kiemeney, Lambertus A., Mariette, Xavier, Richard-Miceli, Corrine, Canhão, Helena, Fonseca, João E., de Vries, Niek, Tak, Paul P., Crusius, J. Bart A., Nurmohamed, Michael T., Kurreeman, Fina, Mikuls, Ted R., Okada, Yukinori, Stahl, Eli A., Larson, David E., Deluca, Tracie L., O'Laughlin, Michelle, Fronick, Catrina C., Fulton, Lucinda L., Kosoy, Roman, Ransom, Michael, Bhangale, Tushar R., Ortmann, Ward, Cagan, Andrew, Gainer, Vivian, Karlson, Elizabeth W., Kohane, Isaac, Murphy, Shawn N., Martin, Javier, Zhernakova, Alexandra, Klareskog, Lars, Padyukov, Leonid, Worthington, Jane, Mardis, Elaine R., Seldin, Michael F., Gregersen, Peter K., Behrens, Timothy, Raychaudhuri, Soumya, Denny, Joshua C., Plenge, Robert M.
Publicado no PLoS One (2015)