A GWAS follow-up study reveals the association of the IL12RB2 gene with systemic sclerosis in Caucasian populations

A single-nucleotide polymorphism (SNP) at the IL12RB2 locus showed a suggestive association signal in a previously published genome-wide association study (GWAS) in systemic sclerosis (SSc). Aiming to reveal the possible implication of the IL12RB2 gene in SSc, we conducted a follow-up study of this...

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Auteurs principaux: Bossini-Castillo, Lara, Martin, Jose-Ezequiel, Broen, Jasper, Gorlova, Olga, Simeón, Carmen P., Beretta, Lorenzo, Vonk, Madelon C., Luis Callejas, Jose, Castellví, Ivan, Carreira, Patricia, José García-Hernández, Francisco, Fernández Castro, Mónica, Coenen, Marieke J.H., Riemekasten, Gabriela, Witte, Torsten, Hunzelmann, Nicolas, Kreuter, Alexander, Distler, Jörg H.W., Koeleman, Bobby P., Voskuyl, Alexandre E., Schuerwegh, Annemie J., Palm, Øyvind, Hesselstrand, Roger, Nordin, Annika, Airó, Paolo, Lunardi, Claudio, Scorza, Raffaella, Shiels, Paul, van Laar, Jacob M., Herrick, Ariane, Worthington, Jane, Denton, Christopher, Tan, Filemon K., Arnett, Frank C., Agarwal, Sandeep K., Assassi, Shervin, Fonseca, Carmen, Mayes, Maureen D., Radstake, Timothy R.D.J., Martin, Javier
Format: Artigo
Langue:Inglês
Publié: Oxford University Press 2012
Sujets:
Association Studies Articles
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3298110/
https://ncbi.nlm.nih.gov/pubmed/22076442
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/hmg/ddr522
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