Expanded Tropism of Primary Human Immunodeficiency Virus Type 1 R5 Strains to CD4(+) T-Cell Lines Determined by the Capacity To Exploit Low Concentrations of CCR5

Por Dejucq, Nathalie, Simmons, Graham, Clapham, Paul R.
Publicado em 1999

Gag Regulates Association of Human Immunodeficiency Virus Type 1 Envelope with Detergent-Resistant Membranes

Por Bhattacharya, Jayanta, Repik, Alexander, Clapham, Paul R.
Publicado em 2006

HIV-1 gp120 Determinants Proximal to the CD4 Binding Site Shift Protective Glycans That Are Targeted by Monoclonal Antibody 2G12

Por Duenas-Decamp, Maria J., Clapham, Paul R.
Publicado em 2010

Human Immunodeficiency Virus Type 1 Envelope Glycoproteins That Lack Cytoplasmic Domain Cysteines: Impact on Association with Membrane Lipid Rafts and Incorporation onto Budding Vi...

Por Bhattacharya, Jayanta, Peters, Paul J., Clapham, Paul R.
Publicado em 2004

Saturation Mutagenesis of the HIV-1 Envelope CD4 Binding Loop Reveals Residues Controlling Distinct Trimer Conformations

Por Duenas-Decamp, Maria, Jiang, Li, Bolon, Daniel, Clapham, Paul R.
Publicado no PLoS Pathog (2016)

Natural Resistance of Human Immunodeficiency Virus Type 1 to the CD4bs Antibody b12 Conferred by a Glycan and an Arginine Residue Close to the CD4 Binding Loop

Por Duenas-Decamp, Maria José, Peters, Paul, Burton, Dennis, Clapham, Paul R.
Publicado em 2008

Determinants Flanking the CD4 Binding Loop Modulate Macrophage Tropism of Human Immunodeficiency Virus Type 1 R5 Envelopes

Por Duenas-Decamp, Maria José, Peters, Paul J., Burton, Dennis, Clapham, Paul R.
Publicado em 2009

Modulation of HIV-1 macrophage-tropism among R5 envelopes occurs before detection of neutralizing antibodies

Por Richards, Kathryn H, Aasa-Chapman, Marlén MI, McKnight, Áine, Clapham, Paul R
Publicado em 2010

Genotypic and functional properties of early infant HIV-1 envelopes

Por Kishko, Michael, Somasundaran, Mohan, Brewster, Frank, Sullivan, John L, Clapham, Paul R, Luzuriaga, Katherine
Publicado em 2011

The W100 pocket on HIV-1 gp120 penetrated by b12 is not a target for other CD4bs monoclonal antibodies

Por Dueñas-Decamp Maria J, O'Connell Olivia J, Corti Davide, Zolla-Pazner Susan, Clapham Paul R
Publicado em 2012-01-01

The W100 pocket on HIV-1 gp120 penetrated by b12 is not a target for other CD4bs monoclonal antibodies

Por Dueñas-Decamp, Maria J, O'Connell, Olivia J, Corti, Davide, Zolla-Pazner, Susan, Clapham, Paul R
Publicado em 2012

Targeted Delivery of Glucan Particle Encapsulated Gallium Nanoparticles Inhibits HIV Growth in Human Macrophages

Por Soto, Ernesto R., O'Connell, Olivia, Dikengil, Fusun, Peters, Paul J., Clapham, Paul R., Ostroff, Gary R.
Publicado no J Drug Deliv (2016)

Biological Analysis of Human Immunodeficiency Virus Type 1 R5 Envelopes Amplified from Brain and Lymph Node Tissues of AIDS Patients with Neuropathology Reveals Two Distinct Tropis...

Por Peters, Paul J., Bhattacharya, Jayanta, Hibbitts, Samantha, Dittmar, Matthias T., Simmons, Graham, Bell, Jeanne, Simmonds, Peter, Clapham, Paul R.
Publicado em 2004

Biological Analysis of Human Immunodeficiency Virus Type 1 R5 Envelopes Amplified from Brain and Lymph Node Tissues of AIDS Patients with Neuropathology Reveals Two Distinct Tropis...

Por Peters, Paul J., Bhattacharya, Jayanta, Hibbitts, Samantha, Dittmar, Matthias T., Simmons, Graham, Bell, Jeanne, Simmonds, Peter, Clapham, Paul R.
Publicado em 2005

HIV-1 non-macrophage-tropic R5 envelope glycoproteins are not more tropic for entry into primary CD4+ T-cells than envelopes highly adapted for macrophages

Por Musich, Thomas, O’Connell, Olivia, Gonzalez-Perez, Maria Paz, Derdeyn, Cynthia A, Peters, Paul J, Clapham, Paul R
Publicado no Retrovirology (2015)

Independent evolution of macrophage-tropism and increased charge between HIV-1 R5 envelopes present in brain and immune tissue

Por Gonzalez-Perez, Maria Paz, O'Connell, Olivia, Lin, Rongheng, Sullivan, W Matthew, Bell, Jeanne, Simmonds, Peter, Clapham, Paul R
Publicado em 2012

Primary Human Immunodeficiency Virus Type 2 (HIV-2) Isolates Infect CD4-Negative Cells via CCR5 and CXCR4: Comparison with HIV-1 and Simian Immunodeficiency Virus and Relevance to...

Por Reeves, Jacqueline D., Hibbitts, Sam, Simmons, Graham, McKnight, Áine, Azevedo-Pereira, José M., Moniz-Pereira, José, Clapham, Paul R.
Publicado em 1999

The Promiscuous CC Chemokine Receptor D6 Is a Functional Coreceptor for Primary Isolates of Human Immunodeficiency Virus Type 1 (HIV-1) and HIV-2 on Astrocytes

Por Neil, Stuart J. D., Aasa-Chapman, Marlen M. I., Clapham, Paul R., Nibbs, Robert J., McKnight, Áine, Weiss, Robin A.
Publicado em 2005

Stromal Down-Regulation of Macrophage CD4/CCR5 Expression and NF-κB Activation Mediates HIV-1 Non-Permissiveness in Intestinal Macrophages

Por Shen, Ruizhong, Meng, Gang, Ochsenbauer, Christina, Clapham, Paul R., Grams, Jayleen, Novak, Lea, Kappes, John C., Smythies, Lesley E., Smith, Phillip D.
Publicado em 2011

Variation in the biological properties of HIV-1 R5 envelopes: implications of envelope structure, transmission and pathogenesis

Por Duenas-Decamp, Maria José, Peters, Paul J, Repik, Alexander, Musich, Thomas, Gonzalez-Perez, Maria Paz, Caron, Catherine, Brown, Richard, Ball, Jonathan, Clapham, Paul R
Publicado em 2010