The Promiscuous CC Chemokine Receptor D6 Is a Functional Coreceptor for Primary Isolates of Human Immunodeficiency Virus Type 1 (HIV-1) and HIV-2 on Astrocytes

The role of coreceptors other than CCR5 and CXCR4 in the pathogenesis of human immunodeficiency virus (HIV) disease is controversial. Here we show that a promiscuous CC chemokine receptor, D6, can function as a coreceptor for various primary dual-tropic isolates of HIV type 1 (HIV-1) and HIV-2. Furt...

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Détails bibliographiques
Auteurs principaux: Neil, Stuart J. D., Aasa-Chapman, Marlen M. I., Clapham, Paul R., Nibbs, Robert J., McKnight, Áine, Weiss, Robin A.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2005
Sujets:
Pathogenesis and Immunity
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1181543/
https://ncbi.nlm.nih.gov/pubmed/16014924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.15.9618-9624.2005
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