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Variation in the biological properties of HIV-1 R5 envelopes: implications of envelope structure, transmission and pathogenesis
HIV-1 R5 viruses predominantly use CCR5 as a coreceptor to infect CD4(+) T cells and macrophages. While R5 viruses generally infect CD4(+) T cells, research over the past few years has demonstrated that they vary extensively in their capacity to infect macrophages. Thus, R5 variants that are highly...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2949073/ https://ncbi.nlm.nih.gov/pubmed/20930940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/fvl.10.34 |
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