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Natural Resistance of Human Immunodeficiency Virus Type 1 to the CD4bs Antibody b12 Conferred by a Glycan and an Arginine Residue Close to the CD4 Binding Loop

The human monoclonal antibody b12 recognizes a conserved epitope on gp120 that overlaps the CD4 binding site. b12 has neutralizing activity against diverse human immunodeficiency virus type 1 (HIV-1) strains. However, we recently reported that b12 sensitivity of HIV-1 envelopes amplified from patien...

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Detalhes bibliográficos
Main Authors: Duenas-Decamp, Maria José, Peters, Paul, Burton, Dennis, Clapham, Paul R.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2395159/
https://ncbi.nlm.nih.gov/pubmed/18385254
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02585-07
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