Dysregulated GPCR Signaling and Therapeutic Options in Uveal Melanoma

di Chua, Vivian, Lapadula, Dominic, Randolph, Clinita, Benovic, Jeffrey L., Wedegaertner, Philip, Aplin, Andrew E.
Pubblicato in Mol Cancer Res (2017)

Co-targeting HGF-cMET signaling with MEK inhibitors in metastatic uveal melanoma

di Cheng, Hanyin, Chua, Vivian, Liao, Connie, Purwin, Timothy J., Terai, Mizue, Kageyama, Ken, Davies, Michael A., Sato, Takami, Aplin, Andrew E.
Pubblicato in Mol Cancer Ther (2017)

The Latest on Uveal Melanoma Research and Clinical Trials: Updates from the Cure Ocular Melanoma (CURE OM) Science Meeting (2019)

di Chua, Vivian, Mattei, Jane, Han, Anna, Johnston, Lauren, LiPira, Kyleigh, Selig, Sara M., Carvajal, Richard D., Aplin, Andrew E., Patel, Sapna P.
Pubblicato in Clin Cancer Res (2020)

Inhibition of NF-κB–Dependent Signaling Enhances Sensitivity and Overcomes Resistance to BET Inhibition in Uveal Melanoma

di Ambrosini, Grazia, Do, Catherine, Tycko, Benjamin, Realubit, Ronald B., Karan, Charles, Musi, Elgilda, Carvajal, Richard D., Chua, Vivian, Aplin, Andrew E., Schwartz, Gary K.
Pubblicato in Cancer Res (2019)

BAP1 mutant uveal melanoma is stratified by metabolic phenotypes with distinct vulnerability to metabolic inhibitors

di Han, Anna, Purwin, Timothy J., Bechtel, Nelisa, Liao, Connie, Chua, Vivian, Seifert, Erin, Sato, Takami, Schug, Zachary T., Speicher, David W., Harbour, J. William, Aplin, Andrew E.
Pubblicato in Oncogene (2020)

Metabolic adaptations to MEK and CDK4/6 co-targeting in uveal melanoma

di Teh, Jessica L.F., Purwin, Timothy J., Han, Anna, Chua, Vivian, Patel, Prem, Baqai, Usman, Liao, Connie, Bechtel, Nelisa, Sato, Takami, Davies, Michael A., Aguirre-Ghiso, Julio, Aplin, Andrew E.
Pubblicato in Mol Cancer Ther (2020)

Stromal fibroblast growth factor 2 reduces the efficacy of bromodomain inhibitors in uveal melanoma

di Chua, Vivian, Orloff, Marlana, Teh, Jessica LF, Sugase, Takahito, Liao, Connie, Purwin, Timothy J, Lam, Bao Q, Terai, Mizue, Ambrosini, Grazia, Carvajal, Richard D, Schwartz, Gary, Sato, Takami, Aplin, Andrew E
Pubblicato in EMBO Mol Med (2019)