Cleaning up the environment in juvenile myelomonocytic leukemia

nork Deng, Lisa, Chan, Rebecca J.
Argitaratua izan da Transl Cancer Res (2017)

PTPN11 is the first identified proto-oncogene that encodes a tyrosine phosphatase

nork Chan, Rebecca J., Feng, Gen-Sheng
Argitaratua 2007

Shp2 function in hematopoietic stem cell biology and leukemogenesis

nork Nabinger, Sarah C., Chan, Rebecca J.
Argitaratua izan da Curr Opin Hematol (2012)

Activating PTPN11 Mutants Promote Hematopoietic Progenitor Cell Cycle Progression and Survival

nork Yang, Zhenyun, Li, Yiping, Yin, Fuqin, Chan, Rebecca J.
Argitaratua 2008

Pharmacologic inhibition of PI3K p110δ in mutant Shp2E76K-expressing mice

nork Deng, Lisa, Virts, Elizabeth L., Kapur, Reuben, Chan, Rebecca J.
Argitaratua izan da Oncotarget (2017)

Novel Method of Murine Embryonic Stem Cell-Derived Osteoclast Development

nork Goodman, Michael L., Chen, Shi, Yang, Feng-Chun, Chan, Rebecca J.
Argitaratua 2009

Mice expressing Kras(G12D) in hematopoietic multipotent progenitor cells develop neonatal myeloid leukemia

nork Tarnawsky, Stefan P., Kobayashi, Michihiro, Chan, Rebecca J., Yoder, Mervin C.
Argitaratua izan da J Clin Invest (2017)

Genetic and pharmacologic evidence implicating the p85α, but not p85β, regulatory subunit of PI3K and Rac2 GTPase in regulating oncogenic KIT-induced transformation in acute myeloi...

nork Munugalavadla, Veerendra, Sims, Emily C., Borneo, Jovencio, Chan, Rebecca J., Kapur, Reuben
Argitaratua 2007

Genetic disruption of the PI3K regulatory subunits, p85α, p55α, and p50α, normalizes mutant PTPN11-induced hypersensitivity to GM-CSF

nork Goodwin, Charles B., Yang, Zhenyun, Yin, Fuqin, Yu, Menggang, Chan, Rebecca J.
Argitaratua 2012

Juvenile Myelomonocytic Leukemia: A Report from the 2(nd) International JMML Symposium

nork Chan, Rebecca J., Cooper, Todd, Kratz, Christian P., Weiss, Brian, Loh, Mignon L.
Argitaratua 2008

Yolk Sac Erythromyeloid Progenitors Expressing Gain Of Function PTPN11 Have Functional Features Of JMML But Are Not Sufficient To Cause Disease In Mice

nork Tarnawsky, Stefan P., Yoshimoto, Momoko, Deng, Lisa, Chan, Rebecca J., Yoder, Mervin C.
Argitaratua izan da Dev Dyn (2017)

Hematopoietic-restricted Ptpn11E76K reveals indolent MPN progression in mice

nork Tarnawsky, Stefan P., Yu, Wen-Mei, Qu, Cheng-Kui, Chan, Rebecca J., Yoder, Mervin C.
Argitaratua izan da Oncotarget (2018)

Human somatic PTPN11 mutations induce hematopoietic-cell hypersensitivity to granulocyte-macrophage colony-stimulating factor

nork Chan, Rebecca J., Leedy, Melissa B., Munugalavadla, Veerendra, Voorhorst, Cara S., Li, Yanjun, Yu, Menggang, Kapur, Reuben
Argitaratua 2005

Rapid development of myeloproliferative neoplasm in mice with Ptpn11(D61Y) mutation and haploinsufficient for Dnmt3a

nork Deng, Lisa, Richine, Briana M., Virts, Elizabeth L., Jideonwo-Auman, Victoria N., Chan, Rebecca J., Kapur, Reuben
Argitaratua izan da Oncotarget (2017)

Tlx3 exerts context-dependent transcriptional regulation and promotes neuronal differentiation from embryonic stem cells

nork Kondo, Takako, Sheets, Patrick L., Zopf, David A., Aloor, Heather L., Cummins, Theodore R., Chan, Rebecca J., Hashino, Eri
Argitaratua 2008

Genetic disruption of the scaffolding protein, Kinase Suppressor of Ras 1 (KSR1), differentially regulates GM-CSF-stimulated hyperproliferation in hematopoietic progenitors express...

nork Yang, Zhenyun, Chen, Mia, Sitarski, Sarah A, Saadatzadeh, Tirajeh, Yin, Fuqin, Yu, Menggang, Yang, Feng-Chun, Chan, Rebecca J
Argitaratua 2011

Wnt signaling promotes neuronal differentiation from mesenchymal stem cells through activation of Tlx3

nork Kondo, Takako, Matsuoka, Akihiro J., Shimomura, Atsushi, Koehler, Karl R., Chan, Rebecca J., Miller, Josef M., Srour, Edward F., Hashino, Eri
Argitaratua 2011

Inhibition of the Gab2/PI3K/mTOR signaling ameliorates myeloid malignancy caused by Ptpn11 (Shp2) gain-of-function mutations

nork Liu, Wei, Yu, Wen-Mei, Zhang, Jing, Chan, Rebecca J., Loh, Mignon L., Zhang, Zheng, Bunting, Kevin D., Qu, Cheng-Kui
Argitaratua izan da Leukemia (2016)

Kinase Suppressor of Ras (KSR1) modulates multiple Kit-ligand-dependent mast cell functions

nork Chen, Mia, Burgin, Sarah, Staser, Karl, He, Yongzheng, Li, Xiaohong, Robinson, Mikella, Jiang, Li, Chan, Rebecca J., Ingram, David, Clapp, D. Wade
Argitaratua 2011

p53 Is Renoprotective after Ischemic Kidney Injury by Reducing Inflammation

nork Sutton, Timothy A., Hato, Takashi, Mai, Erik, Yoshimoto, Momoko, Kuehl, Sarah, Anderson, Melissa, Mang, Henry, Plotkin, Zoya, Chan, Rebecca J., Dagher, Pierre C.
Argitaratua 2012